What are the Disadvantages of Mifepristone?

Ethics

RU-486 is only effective during the earliest weeks of pregnancy, a time when many woman do not yet know when they are pregnant.
RU-486 takes longer than a surgical abortion. A vacuum aspiration abortion is done in 15 minutes, whereas RU-486 takes two days or more and, at present, requires two trips to the clinic for the abortion itself.
As a relatively new procedure, the long term safety of RU-486 cannot yet be confirmed.