Cśruloplasmin - the Pathology

Motor Neurone Disease

Or amyotrophic lateral sclerosis (ALS), is a progressive, fatal neurological disease affecting as many as 2 people in 100,000. Copper is implicated via a mutant of superoxide dismutase. In the U.S., ALS is known as Lou Gehrig's disease due to the fact that the famous baseball player, Lou Gehrig, died from the disease in 1941. The most famous person living with ALS is noted British physicist Stephen Hawking. He has been living with ALS for more than 35 years. He is able to move only two fingers. ALS was first described in scientific literature in 1869 by the French neurologist Jean-Martin Charcot. The French refer to ALS as Maladie de Charcot.