Cæruloplasmin - the Pathology

Wilson's Disease

Kayser-Fleischer Ring Is a genetic disorder that causes excessive copper accumulation in the liver or brain. It affects about one in thirty thousand people worldwide. Over 90% of Wilson's Disease patients have abnormally low levels of blood ceruloplasmin. Kayser-Fleischer Rings, a brownish-yellow ring in the outer rim of the cornea of the eye, and due to a deposit of copper granules, is a diagnostic of Wilson's Disease - but not always