Active Ingredients.

Sunscreens have been traditionally divided into chemical absorbers and physical blockers based on their mechanism of action. Chemical sunscreens are generally aromatic compounds conjugated with a carbonyl group. These chemicals absorb high intensity UV rays with excitation to a higher energy state. The energy lost results in conversion of the remaining energy into longer lower energy wavelengths with return to ground state. Physical blockers reflect or scatter UVR.

Allowable ingredients as listed in the FDA monograph, as are maximum allowable concentrations, are shown in the table, along with their maximum allowable concentration. Sunscreen ingredients can also be classified by the portion of UVR they effectively absorb.

Drug Name

Conc. %

Absorbance

Aminobenzoic acid

Up to 15

UVB

Avobenzone

2-3

UVAI

Cinoxate

Up to 3

UVB

Dioxybenzone

Up to 3

UVB, UVAII

Homosalate

Up to 15

UVB

Menthyl anthranilate

Up to 5

UVAII

Octocrylene

Up to 10

UVB

Octyl methoxycinnamate

Up to 7.5

UVB

Octisalate

Up to 5

UVB

Oxybenzone

Up to 6

UVB, UVAII

Padimate O

Up to 8

UVB

Phenylbenzimidazole sulfonic acid

Up to 4

UVB

Sulisobenzone

Up to 10

UVB, UVAII

Titanium dioxide

2 to 25

Physical

Trolamine salicylate

Up to 12

UVB

Zinc oxide

2 to 20

Physical

To view some of the above structures, please click here.

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