| Vitamin B1
Vitamin B1 in the Body
Crystals of Vitamin B1
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Vitamin B1Other names for the water soluble vitamin B1 are thiamine, antiberiberi factor, aneurine and antineuritic factor.
Thiamine pyrophosphate is the biochemically active ester of thiamine, involved in many important metabolic processes including:
Fig.1 The Chemical Structure of Vitamin B1 (thiamine hydrochloride)
3D Structure of Thiamine
Principal Sources in FoodAlthough thiamine occurs widely in foods, it is generally in small amounts. The principal source of thiamine is in dried brewers yeast and there are other good sources including:
Vitamin B1 in the BodyThiamine is essential in the body for the releasing of energy from carbohydrate and fat, and is also involved in conduction of nerve impulses. It is not stored well in the body (highest concentrations being in the brain, heart, liver and kidney) and so a continuous supply is required. Deficiency results in two diseases:
Did You Know? Beriberi translated into English means 'I can't, I can't'.
StabilityVitamin B1 is sensitive to heat, alkali, oxygen and radiation and considerable amounts of the vitamin can be lost during cooking.
SynthesisChemical synthesis of thiamine is very complicated, involving 15-17 different steps.