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Anaphylaxis: Acute allergic reaction

 

Angioedema: Rapid swelling (edema) of the tissues under the skin

 

Antibody: A protein naturally made by the body to fight infection (foreign in nature) and kill bacteria.

 

Anthracycline: A chemotherapy drug used to treat a wide range of cancers.

 

Arthralgia: Joint pain

 

Asthenia: A feeling of weakness with loss of energy and strength

 

Cardiotoxicity: Toxicity that affects the heart. 

 

Gene: The basic unit of heredity, composed of DNA.

 

HER2: Human epidermal growth factor receptor 2, found on the surface of cells

 

Hypersensitivity: An exaggerated immune response to a foreign body

 

Hypertension: A high blood pressure

 

Hypotension: A low blood pressrue

 

Inhibitor: The key component of a lock and key model. It is a substance that can fit in and bind to a receptor (or a protien for example) but does not cause a change in activity of the cell, or protien.

 

Matastatic cancer: Cancer that has spead from its origial source. Cells can break off from one tumour and form another (metastases).

Monoclonal Antibodies: Engineered antibodies from a biological species, for example a mouse.

Myalgia: Muscle pain

Receptor: A molecule in or on the surface of a cell which selectively binds an antigen, drug or homone etc which ultimately changes the function of that cell. It is the lock component of a lock and key model.

Taxane: An anticancer drug which stops cell division through inhibition of cellular growth.

 

Urticaria: Chronic hives on the surface of the skin, from an allergic reaction