UBIQUITIN

General

Human ubiquitin in tables

 

Physico - chemical properties [19,20,32]:

Feature/Propertiary

Value

Molecular Weight

 8579,94 [g/mol]

Number of Amino Acids Residues

76

Molar Extinction Coefficient [ελ = 280 nm]

1280 [l/(mmol·cm)]

A280  = 1

6,69 [mg/ml]

Isoelectric Point [pI]

6,79

Charge at pH = 7

- 0,14

 

Amino Acids composition [19,20,32]:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Types of Amino Acids [19,20,32]:

 

 

 

 

 

 

 

 

 

NMR - chemical shifts of ubiquitin:

 

Click here

 

X-Ray diffraction data [33]:

 

 

 

 

 

 

 

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General

References

Biological

Functions

Ubiquitilation

Structure

Amino Acids

Amounth of residues

% by weight

% by amount

A (Ala)

2

1,80

2,63

R (Arg)

4

7,03

5,26

N (Asn)

2

2,66

2,63

D (Asp)

5

6,71

6,58

C (Cys)

0

0,00

0,00

Q (Gln)

6

8,84

7,89

E (Glu)

6

8,90

7,89

G (Gly)

6

4,54

7,89

H (His)

1

1,56

1,32

I (Ile)

7

9,26

9,21

L (Leu)

9

11,91

11,84

K (Lys)

7

10,32

9,21

M (Met)

1

1,50

1,32

F (Phe)

2

3,33

2,63

P (Pro)

3

3,48

3,95

S (Ser)

3

3,18

3,95

T (Thr)

7

8,41

9,21

W (Trp)

0

0,00

0,00

Y (Tyr)

1

1,83

1,32

V (Val)

4

4,73

5,26

Amino Acid Type

Amino Acids

Amounth of residues

% by weight

% by amount

Charged

CDEHKRY

24

36,35

31,58

Polar

CNQSTY

19

24,92

25,00

Hydrophobic

AILFWV

24

31,02

31,58

Acidic

DE

11

15,61

14,47

Basic

KR

11

17,35

14,47

Space group:

P212121

Unit cell dimesions

a = 50.84 Å; b = 42.77 Å; c = 28.95 Å

Angles

α = 90.00o; β = 90.00o; γ = 90.00o

Resolution

1.80 Å

R-Value

0.176

PDB accession code

1ubq