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![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Vitamin D Crystals Copied without permission from Roche Product Information |
Vitamin DVitamin D, or calciferol, is the general name for a collection of steroid-like substances including vitamin D2, ergocalciferol (fig.1) and vitamin D3, cholecalciferol (fig.2). Found only in animal sources, vitamin D is fat soluble and can be manufactured by the body on exposure to UV radiation.Top Chemical Structures![]() Fig.1 The Chemical Structure of Vitamin D2 (Ergocalciferol) 3D Structure of Vitamin D2 ![]() Fig.2 The Chemical Structure of Vitamin D3 ![]() Fig.3 The Chemical Structure of Calcidiol ![]() Fig.4 The Chemical Structure of Calcitriol Top Principal Sources in FoodVitamin D is only found naturally in animals and animal products; fruit and nuts contain no vitamin D at all. Richest sources include:
Did You Know? In many countries, products such as milk, margarine and vegetable oil are fortified with vitamin D, and provide a significant dietary source of the vitamin. Top Vitamin D in the BodyIn the body, the vitamin D is converted to its active hormone form by the liver and the kidney. The calciferol is converted to 25-hydroxycholecalciferol, calcidiol (fig.3), and then metabolized by the kidney to several active forms including 1,25-dihydroxycholecalciferol, calcitriol (fig.4).The main function of vitamin D in the body is to maintain blood levels of calcium and phosophorus. Vitamin D is essential for the absorption of these substances from the small intestine, and also for the mineralization process of the bones. The result of vitamin D deficiency is rachitis (rickets) in children and osteomalacia in adults. Top StabilityAs one of the fat soluble vitamins, vitamin D is stable in food storage, cooking and processing.Top SynthesisCholecalciferol is manufactured by irradiating 7-dehydrocholesterol with ultraviolet light. The production of ergocalciferol is similar, using a starting product of ergosterol, a yeast extract.Top |