Organocatalytic Asymmetric Michael Reaction of Cyclic 1,3-Dicarbonyl Compounds and Unsaturated Ketones
- A Highly Atom-Economic Catalytic One-Step Formation of Optically Active Warfarin Anticoagulant,
N.Halland, T.Hansen and K.A.Jørgensen, Angew. Chem. Int. Ed. 2003, 42(40), 4955.
Studies on 4-Hydroxycoumarins. V. The Condensation of alpha,beta-Unsaturated Ketones with 4-Hydroxycoumarin.
M. Ikawa, M.A. Stahmann and K.P.Link, J.Amer.Chem.Soc 1944, 66, 902.
Warfarin by Yunas Bhonoah of
Imperial College. A student project. The crystal structure paper was not found, nor the differing effects of the two
enantiomers. However see the section on the mechanism of action of Warfarin