2000-2009

Hindered Ureas as Masked Isocyanates: Facile Carbamoylation of Nucleophiles under Neutral Conditions; Marc Hutchby, Chris E. Houlden, J. Gair Ford, Simon N. G. Tyler, Michel R. Gangé, Guy C. Llyod-Jones, Kevin I. Booker-Milburn* Angew. Chem. Int. Ed. 2009, 48, 8721-8724. DOI.

Reaction Control in Synthetic Organic Photochemistry: Switching between [5+2] and [2+2] Modes of Cycloaddition; Claudio Roscini, Kara L. Cubbage, Malcom Berry, Andrew J. Orr-Ewing, Kevin I. Booker-Milburn*, Angew. Chem. Int. Ed. 2009, 48, 8716-8720. DOI.

First Higher-Order Photocycloaddition to a C=N Bond: 1,3-Diazepines from Maleimides; Kara L. Cubbage, Kevin I. Booker-Milburn, Andrew J. Orr-Ewing, Angew. Chem. Int. Ed. 2009, 48, 2514-2517. DOI.

Room-Temperature Palladium-Catalyzed C-H Activation: ortho-Carbonylation of Aniline Derivatives; Chris E. Houlden, Marc Hutchby, Chris D. Bailey, J. Gair Ford, Simon N. G. Tyler, Michel R. Gagné, Guy C. Lloyd-Jones and Kevin I. Booker-Milburn*, Angew. Chem. Int. Ed. 2009, 48, 1830-1833. DOI.

Distinct Reactivity of Pd(OTs)2: The Intermolecular Pd(II)-Catalyzed 1,2-Carboamination of Dienes; C. E. Houlden, C. D. Bailey, G. Ford, M. Gagné, G. C. Lloyd-Jones, K. Booker-Milburn. J. Am. Chem. Soc. 2008,130, 10066-10067. DOI.

A Protecting Group Free Total Synthesis of (±)-Neostenine via the [5 + 2] Photocycloaddition of Maleimides; Michael D. Lainchbury, Marcus I. Medley, Piers M. Taylor, Paul Hirst, Wolfgang Dohle, Kevin I. Booker-Milburn,* J. Org. Chem. 2008, 73, 6497-6505. DOI.

Product Selection through Photon Flux: Laser-Specific Lactone Synthesis; Claudio Roscini, David M. E. Davies, Malcolm Berry, Andrew J. Orr-Ewing,* Kevin I. Booker-Milburn* Angew. Chem. Int. Ed. 2008, 47, 2283-2286. DOI.

Acid-Catalyzed Rearrangement of Fused Alkylideneoxetanols; Paul J. Hickford, James R. Baker, Ian Bruce, Kevin I. Booker-Milburn* Org. Lett. 2007, 9, 4681-4684. DOI.

A chemo- and regio-selective three-component dihydropyrimidinone synthesis ; Chris D. Bailey, Chris E. Houlden, Grégory L. J. Bar, Guy C. Lloyd-Jones and Kevin I. Booker-Milburn,* Chem. Commun. 2007, 2932-4. DOI.

Actinorhodin Biosynthesis: Structural Requirements for Post-PKS Tailoring Intermediates Revealed by Functional Analysis of ActVI-ORF1 Reductase: Takayuki Itoh,Takaaki Taguchi, Meriel R. Kimberley, Kevin I. Booker-Milburn, G. Richard Stephenson, Yutaka Ebizuka, Koji Ichinose,* Biochemistry, 2007, 46, 8181-8188. DOI.

The Intramolecular Photometathesis of Pyrroles; Luke D. Elliot, Malcolm Berry, Andrew J. Orr-Ewing, and Kevin I. Booker-Milburn* J. Am. Chem. Soc., 2007, 129, 3078-3079. DOI.

Use of Temporary Tethers in the Intramolecular [2+2] Photocycloaddition Reactions of Tetrahydrophthalimide Derivatives: A New Approach to Complex Tricyclic Lactones; Şirin Gülten, Andrew Sharpe, James R. Baker, Kevin I. Booker-Milburn* Tetrahedron 2007, 63, 3659-3671. DOI.

Reaction Optimization and Mechanism in Maleimide [5 + 2] Photocycloaddition: A Dual Approach Using Tunable UV Lasers and Time-Dependent DFT; David M. E. Davies, Craig Murray, Malcolm Berry, Andrew. J. Orr-Ewing* and Kevin I. Booker-Milburn* J. Org. Chem. 2007, 72, 1449-1457. DOI.

Copper-Catalysed meso-Bislactone Ring Opening Using Grignard and Mixed Triorganozinc Reagents; Scott Borthwick, Wolfgang Dohle, Paul R. Hirst and Kevin I. Booker-Milburn* Tetrahedron Lett. 2006, 47, 7205-7208. DOI.

A Practical Flow Reactor for Continuous Organic Photochemistry; Benjamin D. A. Hook, Wolfgang Dohle, Paul. R. Hirst, Mark Pickworth, Malcolm B. Berry, Kevin I. Booker-Milburn* J. Org. Chem. 2005, 70, 7558-7564. DOI.

Pd(II)-Catalyzed Intermolecular 1,2-Diamination of Conjugated Dienes; Grégory L. J. Bar, Guy C. Lloyd-Jones,* and Kevin I. Booker-Milburn* J. Am. Chem. Soc. 2005, 127, 7308-7309. DOI.

41. Enantioselective Reduction of β-Keto-Acids Using Engineered S. coelicolor; K. I. Booker-
Milburn,* R. Gillan, M. R. Kimberley, T. Taguchi, K. Ichinose, G. R. Stephenson, Y. Ebizuka,
D. A. Hopwood, Angewandte Chemie. Int. Ed., 2005, 44, 1121.
DOI

40. Remarkably Different Structures and Reaction Mechanisms of Ketoreductases for the Opposite
Stereochemical Control in the Biosynthesis of BIQ Antibiotics, T. Taguchi, K. Kunieda, M.
Takeda-Shitaka, D. Takaya, N. Kawano, M. R. Kimberley, K. I. Booker-Milburn, G. R.
Stephenson, H. Umeyama, Y. Ebizuka, and K. Ichinose,* Bioorg. Med. Chem., 2004, 12, 5917-
5927
DOI

39. Rapid Access to Azepine-Fused Oxetanols from Alkoxy-Substituted Maleimides; K. I. Booker-
Milburn,* J. R. Baker, I. Bruce, Org. Lett., 2004; 6, 1481-1484.
DOI

38. Structure and Biosynthetic Implication of (S)-NHAB, a Novel Shunt Product, from a Disruptant
of the actVI-ORFA Gene for Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2); M.
Ozawa, T. Taguchi, T. Itoh, Y. Ebizuka, K. I. Booker-Milburn, G. R. Stephenson and K.
Ichinose* Tetrahedron, 2003, 59, 8793.

37. Ritter Type Reactions of N-Chlorosaccharin: A Method for the Electrophilic Diamination of
Alkenes, K.I. Booker-Milburn,* D. Guly, B. Cox and P.A. Procopiou Org. Lett., 2003, 3313.

36. Synthesis of the Reported Structures for Pogostol and Pogostol O-Methyl Ether: A Concise
Total Synthesis of Kessane, K. I. Booker-Milburn,* H. Jenkins and P. Mohr, Org. Lett., 2003,
5, 3309.

35. A Rapid Stereocontrolled Entry to the ABCD Tetracyclic Core of Neotuberostemonine; K. I.
Booker-Milburn,* P. Hirst, J. P. H. Charmant and L. H. J. Taylor, Angew. Chem. Int. Ed., 2003,
42, 1642.

34. New Fe(III)-Mediated Radical Cascade Reactions of Cyclopropyl Silyl Ethers; K. I. Booker-
Milburn,* J.L. Jones, G.E.M. Sibley, R. Cox, and J. Meadows, Org. Lett., 2003, 5, 1107.

33. Photochemistry of Benzotriazole: An Unprecedented Tautomer-Selective Intermolecular [2+2]
Photocycloaddition K. I. Booker-Milburn,* P. M. Wood, R. F. Dainty, A.J. White, M. W.
Urquhart, H. J. Lyon, J. P. H. Charmant, Org. Lett., 2002, 4, 1487.

32. Formal Intramolecular [5+2] Photocycloaddition Reactions of Maleimides: A Novel Approach
to the CDE Ring Skeleton of (-)-Cephalotaxine L. F. Dudin, K.I. Booker-Milburn,* C.E.
Anson, and S.D. Guile, Org. Lett., 2001, 3, 3005.

31. Intramolecular Photocycloaddition of N-Alkenyl Substituted Maleimides: A Potential Tool for
the Rapid Construction of Perhydroazaazulene Alkaloids, K.I. Booker-Milburn,* C.E. Anson,
C. Clissold, N.J. Costin, R.F. Dainty, M. Murray, D. Patel and A. Sharpe, Eur. J. Org. Chem.,
2001, 1473.

30. A New Claisen Sequence for the Synthesis of 3-Substituted-2-Oxindoles, K.I. Booker-
Milburn,* M.Fedouloff, S.J.Paknoham, J.B.Strachan, J.L. Melville and M. Voyle Tetrahedron
Lett., 2000, 39, 4657.

29. Fe(III)/Cu(II) Mediated 5- and 6-Exo Oxidative Ring Expansion/Cyclisation of Cyclopropyl
Ethers: Studies Towards Dictyol C and α-Eudesmol, K.I. Booker-Milburn,* B. Cox, M. Grady,
F. Halley, S. Marrison Tetrahedron Lett., 2000, 39, 4651.

28. Chemical Characterisation of Disruptants of S.coelicolor A3(2) actVI Genes Involved in
Actinorhodin Biosynthesis , K. Ichinose,* C. Surti, T. Taguchi, F. Malpartida, K.I. Booker-
Milburn, G. R. Stephenson, Y. Ebizuka and D.A. Hopwood, J. Antibiot., 2000, 53, 144.

27. Genetic Engineering of Streptomyces coelicolor A3(2) for the Enantioselective Reduction of
Unnatural β-Keto-Ester Substrates, C.E. Anson, M.J. Bibb, K.I. Booker-Milburn,* C. Clissold,
P.J. Haley, D. A. Hopwood, K. Ichinose, W. P. Revill, G.R. Stephenson, C.M. Surti, Angew.
Chem. Int. Ed. Engl., 2000, 39, 224.