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The Acetylcholine Receptor | |||
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Mechanism of Synaptic Transmission
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Acetlycholine receptors are multi-subunit membrane spanning protiens. The protiens consist of five distinct subunits; (a,b,d,g). Acetylcholine binds to the a subunits, of which there are two on each of the acetylcholine receptor ion channels. Once bound acetylcholine causes ligand-gated ion channels in the post synaptic membrane to open.
These channels are relatively non-selective so the passage of different
ions, such as Na+, K+ and Li+ occurs
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Taken from: www.colorado.edu/MCDB/ MCDB1150/ohd/overhead.html
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