Publication List

2017

313. ortho-Directing Chromium Arene Complexes as Efficient Mediators for Enantiospecific sp2–sp3 Cross-Coupling Reactions
R. Bigler, V. K. Aggarwal
Angew. Chem. Int. Ed., 2017, Accepted Article. doi
312. Pinacolborane: Second Update [Review]
V. K. Aggarwal, D. J. Blair, E. L. Myers
in e-EROS Encyclopedia of Reagents for Organic Synthesis, 2017. doi
311. Gilbert Stork (1921–2017)
E. Nakamura, J. D. Winkler, V. K. Aggarwal
Angew. Chem. Int. Ed., 2017, Early View. doi
310. Stereocontrolled synthesis of polypropionate fragments based on a building block assembly strategy using lithiation-borylation methodologies
A. Millán, P. Grigol Martínez, V. K. Aggarwal
Chem. Eur. J., 2017, Accepted Article. doi
309. Enantiospecific sp2–sp3 Coupling of o- and p-Phenols with Secondary and Tertiary Boronic Esters
C. M. Wilson, V. Ganesh, A. Noble, V. K. Aggarwal
Angew. Chem. Int. Ed., 2017, Accepted Article. doi
308. Synthesis of Alfaprostol and PGF through 1,4-Addition of an Alkyne to an Enal Intermediate as the Key Step
H. Baars, M. J. Classen, V. K. Aggarwal
Org. Lett., 2017, 19, 6008–6011. doi
307. Homologation of Boronic Esters with Lithiated Epoxides
R. J. Armstrong, V. K. Aggarwal
Org. Synth., 2017, 94, 234-251. doi
306. Stereospecific Allylic Functionalization: The Reactions of Allylboronate Complexes with Electrophiles
C. Garcia-Ruiz, J. L.-Y. Chen, C. Sandford, K. Feeney, P. Lorenzo, G. Berionni, H. Mayr, V. K. Aggarwal
J. Am. Chem. Soc., 2017, 139, 15324–15327. doi | pdf
Featured in Chemistry Views
305. Asymmetric Synthesis of Secondary and Tertiary Boronic Esters [Review]
B. S. L. Collins, C. M. Wilson, E. L. Myers, V. K. Aggarwal
Angew. Chem. Int. Ed., 2017, 56, 11700–11733. doi
304. α-Sulfinyl Benzoates as Precursors to Li and Mg Carbenoids for the Stereoselective Iterative Homologation of Boronic Esters
G. Casoni, M. Kucukdisli, J. M. Fordham, M. Burns, E. L. Myers, V. K. Aggarwal
J. Am. Chem. Soc., 2017, 139, 11877–11886. doi | pdf
303. Asymmetric Synthesis of Tertiary Alcohols and Thiols via Non-Stabilized Tertiary α-Oxy- and α-Thio-Organolithiums
A. P. Pulis, A. Varela, C. Citti, P. Songara, D. Leonori, V. K. Aggarwal
Angew. Chem. Int. Ed., 2017, 56, 10835-10839. doi | pdf
Selected as Hot Paper
Highlighted in Synfacts doi | pdf
302. Synergy of synthesis, computation and NMR reveals correct baulamycin structures
J. Wu, P. Lorenzo, S. Zhong, M. Ali, C. P. Butts, E. L. Myers, V. K. Aggarwal
301. 50 Years of Zweifel Olefination: A Transition-Metal-Free Coupling [Review]
R. J. Armstrong, V. K. Aggarwal
Synthesis, 2017, 49, 3323–3336. doi | pdf
300. Enantioselective Rhodium(III)-Catalyzed Markovnikov Hydroboration of Unactivated Terminal Alkenes
J. R. Smith, B. S. L. Collins, M. J. Hesse, M. A. Graham, E. L. Myers, V. K. Aggarwal
J. Am. Chem. Soc., 2017, 139, 9148–9151. doi | pdf
Highlighted in OPRD
Highlighted in Synfacts doi | pdf
299. Enantiospecific Synthesis of ortho-Substituted Benzylic Boronic Esters by a 1,2-Metalate Rearrangement/1,3-Borotropic Shift Sequence
S. Aichhorn, R. Bigler, E. L. Myers, V. K. Aggarwal
J. Am. Chem. Soc., 2017, 139, 9519–9522. doi | pdf
Featured in SYNFACTS doi | pdf
298. Alkynyl Moiety for Triggering 1,2-Metallate Shifts: Enantiospecific sp2-sp3 Coupling of Boronic Esters with p-Arylacetylenes
V. Ganesh, M. Odachowski, V. K. Aggarwal
Angew. Chem. Int. Ed., 2017, 56, 9752–9756. doi | pdf
297. Photoinduced decarboxylative borylation of carboxylic acids
A. Fawcett, J. Pradeilles, Y. Wang, T. Mutsuga, E. L. Myers, V. K. Aggarwal
Science, 2017, 357, 283–286. doi | pdf
296. Synthesis of Functionalized Alkenes by a Transition-Metal-Free Zweifel Coupling
R. J. Armstrong, W. Niwetmarin, V. K. Aggarwal
Org. Lett., 2017, 19, 2762–2765. doi
Featured in SYNFACTS
Highlighted in OPRD
295. Conjunctive functionalization of vinyl boronate complexes with electrophiles: a diastereoselective three-component coupling
R. J. Armstrong, C. Sandford, C. García-Ruiz, V. K. Aggarwal
Chem. Commun., 2017, 53, 4922–4925. doi | pdf
294. Merging Photoredox with 1,2-Metallate Rearrangements: The Photochemical Alkylation of Vinyl Boronate Complexes
M. Silvi, C. Sandford, V. K. Aggarwal
J. Am. Chem. Soc., 2017, 139, 5736–5739. doi | pdf
293. Iterative assembly line synthesis of polypropionates with full stereocontrol
T. Bootwicha, J. M. Feilner, E. L. Myers, V. K. Aggarwal
Nature Chem., 2017, 9, 896–902. doi
292. Stereospecific functionalizations and transformations of secondary and tertiary boronic esters [Review]
C. Sandford, V. K. Aggarwal
Chem. Commun., 2017, 53, 5481–5494. doi | pdf
Selected as the inside cover of the issue.
291. Selective uni- and bidirectional homologation of diborylmethane
D. J. Blair, D. Tanini, J. M. Bateman, H. K. Scott, E. L. Myers, V. K. Aggarwal
Chem. Sci., 2017, 2898–2903. doi | pdf
290. Enantiospecific Trifluoromethyl-Radical-Induced Three-Component Coupling of Boronic Esters with Furans
Y. Wang, A. Noble, C. Sandford, V. K. Aggarwal
Angew. Chem. Int. Ed., 2017, 56, 1810–1814. doi | pdf
289. Stereocontrolled Total Synthesis of (−)-Stemaphylline
A. Varela, L. K. B. Garve, D. Leonori, V. K. Aggarwal
Angew. Chem. Int. Ed., 2017, 56, 2127–2131. doi | pdf
288. Stereodivergent Olefination of Enantioenriched Boronic Esters
R. J. Armstrong, C. García-Ruiz, E.L. Myers, V. K. Aggarwal
Angew. Chem. Int. Ed., 2017, 56, 786–790. doi | pdf
Selected as Hot Paper

2016

287. (2-Bromoethyl)diphenylsulfonium Trifluoromethanesulfonate
J. V. Matlock, V. K. Aggarwal, E. M. McGarrigle
in e-EROS Encyclopedia of Reagents for Organic Synthesis, 2016. doi
(2-Bromoethyl)diphenylsulfonium Trifluoromethanesulfonate
286. Short Enantioselective Total Synthesis of Tatanan A and 3-epi-Tatanan A Using Assembly-Line Synthesis
A. Noble, S. Roesner, V. K. Aggarwal
Angew. Chem. Int. Ed., 2016, 55, 15920–15924. doi | pdf
285. Regio- and Stereoselective Homologation of 1,2-Bis(Boronic Esters): Stereocontrolled Synthesis of 1,3-Diols and Sch 725674
A. Fawcett, D. Nitsch, M. Ali, J. M. Bateman, E. L. Myers, V. K. Aggarwal
Angew. Chem. Int. Ed., 2016, 55, 14663–14667. doi | pdf
284. Development of Enantiospecific Coupling of Secondary and Tertiary Boronic Esters with Aromatic Compounds
M. Odachowski, A. Bonet, S. Essafi, P. Conti-Ramsden, J. N. Harvey, D. Leonori, V. K. Aggarwal
J. Am. Chem. Soc., 2016, 138, 9521–9532. doi | pdf
Featured in SYNFACTS doi | pdf
283. Synthesis of 3-Aryl-1-aminopropane Derivatives: Lithiation–Boryl­ation–Ring-Opening of Azetidinium Ions
G. Casoni, E. L. Myers, V. K. Aggarwal
Synthesis, 2016, 48, 3241-3253. doi | pdf
282. Full chirality transfer in the synthesis of hindered tertiary boronic esters under in situ lithiation–borylation conditions
D. J. Blair, S. Zhong, M. J. Hesse, N. Zabaleta, E. L. Myers, V. K. Aggarwal
Chem. Commun., 2016, 52, 5289–5292. doi | pdf
281. Enantiospecific Alkynylation of Alkylboronic Esters
Yahui Wang, Adam Noble, Eddie L. Myers, Varinder K. Aggarwal
Angew. Chem. Int. Ed., 2016, 55, 4270–4274. doi | pdf
Featured in SYNFACTS doi | pdf
280. Tandem Allylboration–Prins Reaction for the Rapid Construction of Substituted Tetrahydropyrans: Application to the Total Synthesis of (−)-Clavosolide A
Alba Millán, James R. Smith, Jack L.-Y. Chen, Varinder K. Aggarwal
Angew. Chem. Int. Ed., 2016, 55, 2498–2502. doi | pdf
Selected as Hot Paper in the Total Synthesis section
279. Activation of the SN2 Reaction by Adjacent π Systems: The Critical Role of Electrostatic Interactions and of Dissociative Character
Raphaël Robiette, Tran Trieu-Van, Varinder K. Aggarwal, and Jeremy N. Harvey.
J. Am. Chem. Soc., 2016, 138, 734–737. doi | pdf
One of the most read JACS articles in Jan 2016.

2015

278. Reagent-Controlled Lithiation–Borylation
D. Leonori, V. K. Aggarwal
in Synthesis and Application of Organoboron Compounds, Topics in Organometallic Chemistry, 2015, 49, 271-295. doi
277. Synthesis of 6- and 7-Membered N-Heterocycles Using α-Phenylvinylsulfonium Salts
Johnathan V. Matlock, Thomas D. Svejstrup, Pradip Songara, Sarah Overington, Eoghan M. McGarrigle, Varinder K. Aggarwal.
Org. Lett., 2015, 17, 5044–5047. doi | pdf
Selected as the Synfact of the Month. doi | pdf
276. Synthesis of Enantioenriched Alkylfluorides by the Fluorination of Boronate Complexes
Christopher Sandford, Ramesh Rasappan, Varinder K. Aggarwal.
J. Am. Chem. Soc., 2015, 137, 10100–10103. doi | pdf
One of top-20 most read articles in JACS in August 2015.
275. Short Convergent Synthesis of the Mycolactone Core Through Lithiation–Borylation Homologations
Christopher A. Brown, Varinder K. Aggarwal.
Chem. Eur. J., 2015, 21, 13900–13903 doi | pdf
274. Stereospecific Coupling of Boronic Esters with N-Heteroaromatic Compounds
Josep Llaveria, Daniele Leonori, Varinder K. Aggarwal.
J. Am. Chem. Soc., 2015, 137, 10958–10961 doi | pdf
One of top-20 most read articles in JACS in August 2015.
Highlighted in Org. Proc. Res. Dev.
273.Structure and Reactivity of Boron-Ate Complexes Derived from Primary and Secondary Boronic Esters
Kathryn Feeney, Guillaume Berionni, Herbert Mayr, Varinder K. Aggarwal.
Org. Lett., 2015, 17, 2614-2617 doi | pdf
272.Enantioselective installation of adjacent tertiary benzylic stereocentres using lithiation–borylation–protodeboronation methodology. Application to the synthesis of bifluranol and fluorohexestrol
Stefan Roesner, Daniel J. Blair, Varinder K. Aggarwal.
Chem. Sci., 2015, 6, 3718-3723 doi | pdf
This paper was highlighted in Synfacts. doi | pdf
271.Palladium-Catalyzed Reactions of Allylic Boronic Esters with Nucleophiles: Novel Umpolung Reactivity
Phillip J. Unsworth, Lorenz E. Löffler, Adam Noble, Varinder K. Aggarwal.
Synlett, 2015, 26, 1567-1572 doi | pdf
270. Synthesis of Prostaglandin Analogues, Latanoprost and Bimatoprost, Using Organocatalysis via a Key Bicyclic Enal Intermediate
Sébastien Prévost, Karen Thai, Nina Schützenmeister, Graeme Coulthard, William Erb, Varinder K. Aggarwal.
Org. Lett., 2015, 17, 504-507 doi | pdf
269.Toward Ideality: The Synthesis of (+)​-​Kalkitoxin and (+)​-​Hydroxyphthioceranic Acid by Assembly-​Line Synthesis
Sebastien Balieu, Gayle E. Hallett, Matthew Burns, Teerawut Bootwicha, John Studley, Varinder K. Aggarwal.
J. Am. Chem. Soc., 2015, 137, 4398-4403 doi | pdf
Selected as a front cover of the issue.
Highlighted in JACS Spotlights. doi | pdf
Highlighted in Synfacts. doi | pdf

2014

268. Lithium–Boron Chemistry: A Synergistic Strategy in Modern Synthesis
C. G. Watson, P. J. Unsworth, D. Leonori, V. K. Aggarwal
in Lithium Compounds in Organic Synthesis, 2014, Ch. 14, 397–422. doi
267. Stereospecific Couplings of Secondary and Tertiary Boronic Esters
D. Leonori, V. K. Aggarwal
Angew. Chem. Int. Ed., 2014, 54, 1082–1096. doi
266. Lithiation–Borylation Methodology and its Application in Synthesis
D. Leonori, V. K. Aggarwal
Acc. Chem. Res., 2014, 47, 3174–3183. doi
265. Oxidation of Carbon–Boron Bonds
T. Chinnusamy, K. Feeney, C.G. Watson, D. Leonori, V.K. Aggarwal
in Comprehensive Organic Synthesis II, 2014, Ch. 7.22, 692–718. doi
264. Total Syntheses of Solandelactones E and F
A. Robinson, C. J. Fletcher, V. K. Aggarwal
in Strategies and Tactics in Organic Synthesis, 2014, Vol. 8, Ch. 1, 1–23. doi
263. Homologation of Boronic Esters with Organolithium Compounds: A Computational Assessment of Mechanism
Stéphanie Essafi, Simone Tomasi, Varinder K. Aggarwal, and Jeremy N. Harvey.
J. Org. Chem., 2014, 79, 12148–12158. doi | pdf
262.Construction of Multiple, Contiguous Quaternary Stereocenters in Acyclic Molecules by Lithiation-Borylation
Charlotte G. Watson, Angelica Balanta, Tim G. Elford, Stéphanie Essafi, Jeremy N. Harvey, Varinder K. Aggarwal.
J. Am. Chem. Soc., 2014, 136, 17370-17373 doi | pdf
261.Synthesis of α-Substituted Vinylsulfonium Salts and Their Application as Annulation Reagents in the Formation of Epoxide- and Cyclopropane-Fused Heterocycles
Johnathan V. Matlock, Sven P. Fritz, Stephen A. Harrison, Diane M. Coe, Eoghan M. McGarrigle, Varinder K. Aggarwal.
J. Org. Chem., 2014, 79, 10226-10239. doi | pdf
260. Assembly-line synthesis of organic molecules with tailored shapes
Matthew Burns, Stéphanie Essafi, Jessica R. Bame, Stephanie P. Bull, Matthew P. Webster, Sébastien Balieu, James W. Dale, Craig P. Butts, Jeremy N. Harvey, Varinder K. Aggarwal.
Nature, 2014, 513, 183-188. doi | pdf
Video illustrating assembly-line synthesis video link | Image
259. Highly Diastereoselective and Enantiospecific Allylation of Ketones and Imines using Borinic Esters: Contiguous Quaternary Stereogenic Centers
Jack L.-Y. Chen, Varinder K. Aggarwal.
Angew. Chem. Int. Ed., 2014, 53, 10992-10996. doi | pdf
VIP article
258. Stereocontrolled Synthesis of 1,5-Stereogenic Centers through Three-Carbon Homologation of Boronic Esters.
Phillip J. Unsworth, Dr. Daniele Leonori, Varinder K. Aggarwal.
Angew. Chem. Int. Ed., 2014, 53, 9846-9850. doi | pdf
VIP article
257. Synthesis of hydroxyphthioceranic acid using a traceless lithiation-borylation-protodeboronation strategy.
Ramesh Rasappan, Varinder Aggarwal.
Nat. Chem., 2014, 6, 810–814. doi | pdf
This paper was highlighted in Synfacts. doi | pdf
256. Enantiospecific sp 2–sp 3 coupling of secondary and tertiary boronic esters.
Amadeu Bonet, Marcin Odachowski, Daniele Leonori, Stephanie Essafi, Varinder Aggarwal.
Nat. Chem., 2014, 6, 584–589. doi | pdf
This paper was highlighted in Synfacts. doi | pdf
255. Highly Selective Allylborations of Aldehydes Using α,α-Disubstituted Allylic Pinacol Boronic Esters.
Matthew J. Hesse, Stéphanie Essafi, Charlotte G. Watson, Jeremy N. Harvey, David Hirst, Christine L. Willis, Varinder Aggarwal.
Angew. Chem. Int. Ed., 2014, 53, 6145–6149. doi | pdf
254. Stereocontrolled Synthesis of Adjacent Acyclic Quaternary-Tertiary Motifs and its Application to a Concise Total Synthesis of (−)-Filiformin.
Daniel J. Blair, Catherine J. Fletcher, Katherine M. P. Wheelhouse, Varinder K. Aggarwal.
Angew. Chem. Int. Ed., 2014, 53, 5552–5555. doi | pdf
This paper was highlighted in synfacts. doi | pdf
253. Short Stereoselective Synthesis of the Phytophthora Universal Mating Hormone α1 Using Lithiation/Borylation Reactions.
Alexander P. Pulis, Philipp Fackler, Varinder K. Aggarwal.
Angew. Chem. Int. Ed., 2014, 53, 4382–4385. doi | pdf
252. Stereospecific conversion of alcohols into pinacol boronic esters using lithiation–borylation methodology with pinacolborane.
Stefan Roesner, Christopher A. Brown, Maziar M. Mohiti, Alexander P. Pulis, Ramesh Rasappan, Daniel J. Blair, Stefanie Essafi, Daniele Leonori and Varinder K Aggarwal.
Chem. Commun., 2014, 50, 4053-4055. doi | pdf
This paper was highlighted in Synfacts. doi | pdf
251. Asymmetric Addition of Chiral Boron-Ate Complexes to Cyclic Imminium Ions
Maziar Mohiti, Constantinos Rampalakos, Kathryn Feeney, Daniele Leonori, Varinder K. Aggarwal.
Chem. Sci., 2014, 5, 602-607. doi | pdf

2013

250. Synthesis of Enantioenriched Tertiary Boronic Esters by the Lithiation/Borylation of Secondary Alkyl Benzoates
Alexander P. Pulis , Daniel J. Blair , Eva Torres , and Varinder K. Aggarwal.
J. Am. Chem. Soc., 2013, 135, 16054–16057. doi | pdf
This paper was highlighted in synfacts. doi | pdf
Paper highlighted on Organic Chemistry Portal.
249. Enantiospecific, Regioselective Cross-Coupling Reactions of Secondary Allylic Boronic Esters
Laetitia Chausset-Boissarie, Kazem Ghozati, Emily LaBine, Jack L.-Y. Chen, Varinder K. Aggarwal, Cathleen M. Crudden.
Chemistry - A European Journal, 2013, 19, 17698–17701. doi | pdf
248. Concise Synthesis of (+)-allo-Kainic Acid via MgI2-Mediated Tandem Aziridine Ring Opening–Formal [3 + 2] Cycloaddition
Giada Arena, C. Chun Chen, Daniele Leonori, Varinder K. Aggarwal
Org. Lett., 2013, 15, 4250–4253. doi | pdf
247. Practical and Highly Selective Sulfur Ylide-Mediated Asymmetric Epoxidations and Aziridinations Using a Cheap and Readily Available Chiral Sulfide: Extensive Studies To Map Out Scope, Limitations, and Rationalization of Diastereo- and Enantioselectivities
Ona Illa, Mariam Namutebi, Chandreyee Saha, Mehrnoosh Ostovar, C. Chun Chen, Mairi F. Haddow, Sophie Nocquet-Thibault, Matteo Lusi, Eoghan M. McGarrigle, Varinder K. Aggarwal.
J. Am. Chem. Soc., 2013, 135, 11951–11966. doi | pdf
246. Efficient Synthesis of Cyclopropane-Fused Heterocycles with Bromoethylsulfonium Salt
Sven P. Fritz, Johnathan V. Matlock1, Eoghan M. McGarrigle, Varinder K. Aggarwal.
Chemistry - A European Journal, 2013, 19, 10827-10831. doi | pdf
This paper was highlighted in synfacts. doi | pdf
245. Highly Diastereo-and Enantioselective Allylboration of Aldehydes using α-Substituted Allyl/Crotyl Pinacol Boronic Esters via in situ Generated Borinic Esters
Jack L.-Y. Chen, Helen K Scott, Matthew J Hesse, Christine L. Willis, Varinder K. Aggarwal.
J. Am. Chem. Soc., 2013, 135, 5316–5319. doi | pdf
244. Stereoselective Total Synthesis of (+)-Giganin and Its C10 Epimer by Using Late-Stage Lithiation–Borylation Methodology
Catherine J. Fletcher, Katherine M. P. Wheelhouse, Prof. Varinder K. Aggarwal.
Angew. Chem. Int. Ed., 2013, 52, 2503-2506. doi | pdf
243. Asymmetric Synthesis of 1-Heteroaryl-1-arylalkyl Tertiary Alcohols and 1-Pyridyl-1-arylethanes by Lithiation–Borylation Methodology
Charlotte G. Watson, Varinder K. Aggarwal.
Org. Lett, 2013, 15, 1346-1349. doi | pdf
This paper was highlighted in synfacts. doi | pdf
242. One-pot synthesis of 2,3,4,5,6-pentasubstituted tetrahydropyrans using lithiation-borylation, allylation and Prins cyclisation reactions.
A. Mahmood, J. R. Suárez, S. P. Thomas, V. K. Aggarwal,
Tetrahedron Letters, 2013, 54, 49–51. doi | pdf

2012

241. Bicyclo[2.2.1]heptan-2-one, 7,7-Dimethyl-1-(1S,3S,4R)-2-thiabicyclo[2.2.1]hept-3-yl-, (1S,4R)
O. Illa, E. M. McGarrigle, V. K. Aggarwal
in e-EROS Encyclopedia of Reagents for Organic Synthesis, 2012 doi
240. Sulfonium, Ethenyldiphenyl-, 1,1,1-Trifluoromethanesulfonate
M. Yar, E. M. McGarrigle, V. K. Aggarwal
in e-EROS Encyclopedia of Reagents for Organic Synthesis, 2012 doi
239. Diastereoselective Synthesis of CF3‐Substituted, Epoxide-Fused Heterocycles with β‐(Trifluoromethyl)vinylsulfonium Salts
S. P. Fritz, T. H. West, E. M. McGarrigle, V. K. Aggarwal.
Org. Lett., 2012, 14, 6370-6373. doi | pdf
238. Diastereo-divergent Synthesis of Trisubstituted Alkenes through Protodeboronation of Allylic Boronic Esters: Application to the Synthesis of the Californian Red Scale Beetle Pheromone.
M. J. Hesse, C. P. Butts, C. L. Willis,  V. K. Aggarwal,
Angew. Chem. Int. Ed., 2012, 51, 12444–12448. doi | pdf
237. Enantioselective Synthesis and Cross-coupling of Tertiary Propargylic Boronic Esters Using Lithiation-Borylation of Propargylic Carbamates.
B. M. Partridge, L. Chausset-Boissarie, M. Burns, A. P. Pulis, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2012, 51, 11795–11799. doi | pdf
This paper was highlighted in synfacts. doi | pdf
236. Bromoethylsulfonium triflates in stereoselective annulation reactions for the formation of fused bicyclic epoxides and aziridines.
S. P. Fritz, Z. Ali, M. G. Unthank, E. M. McGarrigle, V. K. Aggarwal,
Helv. Chim. Acta (Prof. D. Seebach special issue), 2012, 95, 2384-2398. doi | pdf
235. Enantioselective Synthesis of (R)-Tolterodine using Lithiation/Borylation Protodeboronation Methodology.
S. Roesner, V. K. Aggarwal,
Can. J. Chem., 2012, 90, 965-974. doi | pdf
234. Stereocontrolled organocatalytic synthesis of prostaglandin PGF in seven steps
G. Coulthard, W. Erb, V. K. Aggarwal,
Nature, 2012, 489, 278-281. doi | pdf
This paper was highlighted in SYNFACTS: Organo- and Biocatalysis (doi) and Synthesis of Natural Products and Potential Drugs (doi)
An excellent short highlight in Nature News has been written by Sorensen (doi | pdf) and Sanderson (url | pdf)
leading news story in C&EN News
233. The total synthesis of (–)-aplysin via a lithiation-borylation-propenylation sequence.
C. J. Fletcher, D. J. Blair, K. M. P. Wheelhouse, V. K. Aggarwal,
Tetrahedron, 2012, 68, 7598-7604. doi | pdf
232. Application of the Lithiation-Borylation Reaction to the Rapid and Enantioselective Synthesis of the Bisabolane Family of Sesquiterpenes.
V. K. Aggarwal, L. T. Ball, S. Carobene, R. L. Connelly, M. J. Hesse, B. M. Partridge, P. Roth, S. P. Thomas, M. P. Webster,
Chem. Commun., 2012, 48, 9230-9232. doi | pdf
231. Synthesis of Enantioenriched Tertiary Boronic Esters from Secondary Allylic Carbamates. Application to the Synthesis of C30 Botryococcene.
A. P. Pulis, V. K. Aggarwal,
J. Am. Chem. Soc., 2012, 134, 7570-7574. doi | pdf
230. An Efficient Synthesis of Azetidines with (2-Bromoethyl)sulfonium Triflate.
S. P. Fritz, J. F. Moya, M. G. Unthank, E. M. McGarrigle, V. K. Aggarwal,
Synthesis, 2012, 44, 1584-1590. doi | pdf
229. Stereocontrolled asymmetric synthesis of syn-E-1,4-diol-2-enes using allyl boronates and its application in the total synthesis of solandelactone F.
A. Robinson, V. K. Aggarwal,
Org. Biomol. Chem, 2012, 10, 1795-1801. doi | pdf
228. Synthesis of N-Vinyloxazolidinones and Morpholines from Aminoalcohols and Vinylsulfonium salts: Analysis of the Outcome’s Dependence on N-Protecting group by Nanospray Mass Spectrometry.
M. Yar, S. P. Fritz, P. J. Gates, E. M. McGarrigle, V. K. Aggarwal,
Eur. J. Org. Chem., 2012, 160-166. doi | pdf

2011

227. Highly Enantioselective Synthesis of Tertiary Boronic Esters and their Stereospecific Conversion to other Functional Groups and Quaternary Stereocentres
H. K. Scott, V. K. Aggarwal
Chem. Eur. J., 2011, 17, 13124-13132. doi | pdf
226. Asymmetric Homologation of Boronic Esters with Lithiated Carbamates, Epoxides, and Aziridines
Matthew P. Webster, Varinder K. Aggarwal
in Boronic Acids: Preparation and Applications in Organic Synthesis, Medicine and Materials, 2011, Vol. 2, Ch. 10, 479-505 doi
225. Enantioenriched Synthesis of Escitalopram using Lithiation-Borylation Methodology.
B. M. Partridge, S. P. Thomas, V. K. Aggarwal,
Tetrahedron, 2011, 67, 10082-10088.  doi | pdf
Paper in honour of Gilbert Stork’s 90th Birthday.
224. Enantioselective Syntheses of (+)-Sertraline and (+) Indatraline using Lithiation/Borylation Protodeboronation Methodology.
S. Roesner, J. M. Casatejada, T. G. Elford, R. P. Sonawane, V. K. Aggarwal,
Org. Lett., 2011, 13, 5740-5743. doi | pdf
This article was among the top 20 accessed articles for the month of October.
This paper was highlighted in synfacts. (pdf)
223. Ate Complexes of Secondary Boronic Esters as Chiral Organometallic-Type Nucleophiles for Asymmetric Synthesis.
R. Larouche-Gauthier, T. G. Elford, V. K. Aggarwal,
J. Am. Chem. Soc., 2011, 133, 16794-16797. doi | pdf
This article was among the top 20 accessed articles for the month of October.
This paper was highlighted in Nature Chemistry. pdf.
This paper was highlighted in synfacts. pdf
222. Total Synthesis of (+)-Erogorgiaene Using Lithiation–Borylation Methodology, and Stereoselective Synthesis of Each of Its Diastereoisomers.
T. G. Elford, S. Nave, R. P. Sonawane, V. K. Aggarwal,
J. Am. Chem. Soc., 2011, 133, 16798-16801. doi | pdf
This paper was highlighted in Synfacts. pdf
221. Use of Alkyl 2,4,6-Triisopropylbenzoates in the Asymmetric Homologation of Challenging Boronic Esters.
R. Larouche-Gauthier, C. J. Fletcher, I. Couto, V. K. Aggarwal,
Chem. Commun., 2011, 47, 12592-12594. doi | pdf
Paper selected as a front issue cover by the Editor.
220. Palladium-Catalyzed Insertion of CO2 into Vinylaziridines: New Route to 5-Vinyloxazolidinones.
F. Fontana, C. C. Chen, V. K. Aggarwal,
Org. Lett., 2011, 13, 3454-3457. doi | pdf
219. An Efficient Synthesis of Imidazolinium Salts using Vinyl Sulfonium Salts.
E. M. McGarrigle, S. P. Fritz, L. Favereau, M. Yar, V. K. Aggarwal
Org. Lett., 2011, 13, 3060-3063. doi | pdf
This paper was highlighted on organic-chemistry.org
218. Sulfinamides as Highly Effective Amine Protecting Groups and their use in the Conversion of Aminoalcohols into Morpholines.
S. P. Fritz, A. Mumtaz, M. Yar, E. M. McGarrigle, V. K. Aggarwal,
Eur. J. Org. Chem., 2011, 2011, 3156-3164. doi | pdf
217. Lithiated Primary Alkyl Carbamates for the Homologation of Boronic Esters.
M. P. Webster, B. M. Partridge, V. K. Aggarwal,
Org. Synth., 2011, 88, 247-259. doi | pdf
Paper selected as the "Featured Article" on the homepage of the Organic Syntheses website.
216. Palladium-Mediated Annulation of Vinyl Aziridines with Michael Acceptors. Stereocontrolled Synthesis of Substituted Pyrrolidines and Application to a Formal Synthesis of (–)-α-Kainic Acid.
M. A. Lowe, M. Ostovar, S. Ferrini, C. C. Chen, P. G. Lawrence, F. Fontana, A. A. Calabrese, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2011, 50, 6370-6374. doi | pdf
215. Remote Chiral Induction in Vinyl Sulfonium Salt-Mediated Ring Expansion of Hemiaminals into Epoxide-Fused Azepines
M. Yar, M. G. Unthank, E. M. McGarrigle, V. K. Aggarwal
Chem. Asian J., 2011, 6, 372–375. doi
214. Enantioselective Construction of Quaternary Stereogenic Centers from Tertiary Boronic Esters: Methodology and Applications.
R. P. Sonawane, V. Jheengut, C. Rabalakos, R. Larouche-Gauthier, H. K. Scott, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2011, 50, 3760-3763. doi | pdf
Very Important Paper (VIP).
Paper selected as a front issue cover by the Editor.
This paper was the subject of an Angewandte Highlight article. This paper was highlighted in synfacts. (pdf)
213. Asymmetric Synthesis of Tertiary and Quaternary Allyl- and Crotylsilanes via the Borylation of Lithiated Carbamates.
V. K. Aggarwal, M. Binanzer, M. Carolina de Ceglie, M. Gallanti, B. W. Glasspoole, S. J. F. Kendrick, R. P. Sonawane, A. Vazquez-Romero, M. P. Webster.
Org. Lett., 2011, 13, 1490-1493. doi | pdf
This paper was highlighted in synfacts. (pdf)
212. Synthesis of Highly Enantioenriched C-Tertiary Amines From Boronic Esters: Application to the Synthesis of Igmesine.
V. Bagutski, T. G. Elford, V. K. Aggarwal.
Angew. Chem. Int. Ed., 2011, 50, 1080-1083. doi | pdf

2010

211. Epoxidation and Aziridination of Carbonyl Groups and Imines
V. K. Aggarwal, E. M. McGarrigle, M. A. Shaw
in Science of Synthesis, G. A. Molander (Ed.), George Thieme Verlag, 2010, Stereoselective Synthesis 2, 311-347. doi
210. Protodeboronation of Tertiary Boronic Esters: Asymmetric Synthesis of Tertiary Alkyl Stereogenic Centers.
S. Nave, R. P. Sonawane, T. G. Elford, V. K. Aggarwal.
J. Am. Chem. Soc., 2010, 132, 17096-17098. doi | pdf
This paper was highlighted at the Organic Synthesis Portal.
209. Ring-opening of NH-Aziridines with Thiols in Ionic Liquids - Application to the Synthesis of Aminosulfide Catalysts for Asymmetric Epoxidation of Aldehydes.
M. Hassan-Namutebi, E. M. McGarrigle, V K. Aggarwal, Phos. Silicon and Sulfur, 2010,185, 1250-1272.
Invited paper for Prof. Naomichi Furukawa's 70th birthday Special Issue.

Abstract: The ring opening of NH-aziridines with thiols was found to proceed in good yield at room temperature in the presence of an ionic liquid---butyl-3-methylimidazolium chloride (BMIM chloride). This mild methodology was applied to the synthesis of a camphor-derived chiral aminosulfide. The sulfide was used to generate a sulfur ylide, which effected an asymmetric epoxidation of benzaldehyde (e.r. 85:15, trans:cis 90:10, 87% yield). The amino group enabled easy recovery of the sulfide (98% yield) after the reaction by a simple acid/base extraction.

208. Asymmetric Total Synthesis of Solandelactone E: Stereocontrolled Synthesis of the 1,4-diol-2-ene core via Lithiation-Borylation-Allylation Sequence
A. Robinson, V. K. Aggarwal
Angew. Chem. Int. Ed., 2010, 49, 6673-6675. doi | pdf
207. Benzylic Boron Reagents Behaving as Allylic Boron Reagents towards Aldehydes: A New Asymmetric Reaction Leading to Homoallylic Alcohols with Concomitant Dearomatisation
A. Ros, A. Bermejo, V. K. Aggarwal,
Chem. Eur. J., 2010, 16, 9741-9745. doi | pdf
206. Synthesis of Quinine and Quinidine using Sulfur Ylide-mediated Asymmetric Epoxidation as a Key Step.
M. Arshad, M. A. Fernández, E. M. McGarrigle, V. K. Aggarwal
Tetrahedron: Asymmetry, 2010, 21, 1771-1776. doi | pdf
205. Synthesis of Highly Functionalized 2,5-Disubstituted Pyrrolidines via an Aza-Morita-Baylis-Hillman-type Reaction.
J. E. Kitulagoda, A. Palmelund, V. K. Aggarwal
Tetrahedron, 2010, 66, 6293-6299 doi | pdf
204. Full Chirality Transfer in the Conversion of Secondary Alcohols into Tertiary Boronic Esters and Alcohols Using Lithiation-Borylation Reactions
V. Bagutski, R. M. French, V. K. Aggarwal
Angew. Chem. Int. Ed., 2010, 49, 5142-5145. doi| pdf
203. On the Mechanism of Ylide-Mediated Cyclopropanations: Evidence for a Proton Transfer Step and its Effect on Stereoselectivity.
S. L. Riches, C. Saha, N. Fontán-Filgueira, E. Grange, E. M. McGarrigle, V. K. Aggarwal
J. Am. Chem. Soc., 2010, 132, 7626-7630. doi | pdf
202. Asymmetric Synthesis of Allylsilanes by the Borylation of Lithiated Carbamates: Formal Total Synthesis of (-)-Decarestrictine D.
M. Binanzer, G. Y. Fang, V. K. Aggarwal
Angew. Chem. Int. Ed., 2010, 49, 4264-4268. doi | pdf
201. A Novel Asymmetric Azaspirocyclisation using a Morita Baylis Hillman-type Reaction.
J. C. Killen, J. Leonard, V. K. Aggarwal
Synlett, 2010, 579-582. doi | pdf
200. Application of the Lithiation-Borylation Reaction to the Preparation of Enantioenriched Allylic Boron Reagents and Subsequent In Situ Conversion into 1,2,4-Trisubstituted Homoallylic Alcohols with Complete Control over All Elements of Stereochemistry.
M. Althaus, A. Mahmood, J. Ramón Suárez, S. P. Thomas, V. K. Aggarwal
J. Am. Chem. Soc., 2010, 132, 4025-4028. doi | pdf
199. Practical and Highly Selective Sulfur Ylide-Mediated Asymmetric Epoxidations and Aziridinations Using a Cheap and Readily Available Chiral Sulfide. Application to the Total Synthesis of Quinine and Quinidine.
O. Illa, M. Arshad, A. Ros, E. M. McGarrigle, V. K. Aggarwal
J. Am. Chem. Soc., 2010, 132, 1828-1830. doi | pdf
Presented in Chemistry By Design.
198. Stereoeselective Synthesis of trans-β-Lactams by Palladium-Catalysed Carbonylation of Vinyl Aziridnes. (pdf, 1.0Mb)
F. Fontana, G. C. Tron, B. Nekane, S. Ferrini, S. P. Thomas, V. K. Aggarwal,
Chem. Commun., 2010, 46, 267-269.
Paper highlighted on Organic Chemistry Portal.

2009

197. Homologation and Alkylation of Boronic Esters and Boranes by 1,2-Metallate Rearrangement of Boron Ate Complexes
S. P. Thomas, R. M. French, V. Jheengut, V. K. Aggarwal
The Chemical Record, 2009, 9, 24-39. doi | pdf
196. Improved Method for the Conversion of Pinacolboronic Esters into Trifluoroborate Salts. Facile Synthesis of Chiral Secondary and Tertiary Trifluoroborates. (pdf)
V. Bagutski, A. Ros, V. K. Aggarwal,
Tetrahedron, 2009, 65, 9956-9960.
195. New Uses for Old Building Blocks
Invited 'News and Views' article.
194. Stereocontrolled Synthesis of Carbon Chains Bearing Contiguous Methyl Groups by Iterative Boronic Ester Homologations. Application to the Total Synthesis of (+)-Faranal. (pdf)
G. Dutheuil, M. P. Webster, P. A. Worthington, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2009, 48, 6317-6319.
Paper invited for cover and highlighted in Synfacts, 2009, 1134; DOI: 10.1055/s-0029-1217846.
193. Complete Stereoretention in the Rhodium-Catalyzed 1,2-Addition of Chiral Secondary and Tertiary Alkyl Potassium Trifluoroborate Salts to Aldehydes. (pdf)
A. Ros, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2009, 48, 6289-6292.
192. The Fate of the tert-Butylsulfinyl Auxiliary After Acid-Promoted Cleavage - a Method for Recycling t-BuSONH2. (pdf)
V. K. Aggarwal, N. Barbero, E. M. McGarrigle, G. Mickle, R. Navas, J. R. Suárez, M. G. Unthank, M. Yar
Tetrahedron Lett., 2009, 50, 3482-3484.
Invited paper for 50th Anniversary Special Issue.
191. Asymmetric Hydroboration of 1,1-Disubstituted Alkenes. (pdf, 1.0Mb)
S. P. Thomas, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2009, 48, 1896-1898.
190. Stereocontrolled Synthesis of β-Amino Alcohols from Lithiated Aziridines and Boronic Esters. (pdf)
F. Schmidt, F. Keller, E. Vedrenne, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2009, 48, 1149-1152.
189. Bromoethylsulfonium salt - a More Effective Annulation Agent for the Synthesis of 6- and 7-Membered 1,4-Diheterocyclic Compounds. (pdf)
M. Yar, E. M. McGarrigle, V. K. Aggarwal,
Org. Lett., 2009, 11, 257-260.
188. Homologation of Boronic Esters with Lithiated Epoxides for the Stereocontrolled Synthesis of 1,2 and 1,3-Diols, and 1,2,4-Triols. (pdf)
E. Vedrenne, O. A. Wallner, M. Vitale, F. Schmidt, V. K. Aggarwal,
Org. Lett. 2009, 11, 165-168.

2008

187. Synthesis of Epoxides by Carbonyl Epoxidation
V. K. Aggarwal, M. Crimmin, S. Riches
in Science of Synthesis, C. Forsyth (Ed.), George Thieme Verlag, 2008, 37, 321-406. doi
186. Highly Enantioselective Conversion of Secondary Alcohols into Tertiary Alcohols with Broad Scope. (pdf, 3.3Mb)
J. L. Stymiest, V. Bagutski, R. M. French, V. K. Aggarwal,
Nature, 2008, 456, 778-782.
185. Synthesis and Application of Easily Recyclable Thiomorpholines for use in Sulfur Ylide-mediated Asymmetric Epoxidation of Aldehydes.
M. Hansch, O. Illa, E. M. McGarrigle, V. K. Aggarwal, Chem. Asian J., 2008, 3, 1657-1663.
184. Sulfur Ylide Mediated Three-Component Aziridination and Epoxidation Reactions Using Vinyl Sulfonium Salts Thre-Component Aziridination and Epoxidation Reaction. (pdf)
C. G. Kokotos, E. M. McGarrigle, V. K Aggarwal,
Synlett, 2008, 2191-2195.
183. Direct Synthesis of Functionalized Allylic Boronic Esters From Allylic Alcohols and Inexpensive Reagents and Catalysts. (pdf)
G. Dutheuil, N. Selander, K. J. Szabó, V. K. Aggarwal,
Synthesis, 2008, 2293-2297.
182. Novel Annulation Reaction for the Synthesis of Morpholines, Thiomorpholines and Piperazines from β-Heteroatom Amino Compounds and Vinyl Sulfonium Salts. (pdf)
M. Yar, E. M. McGarrigle, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2008, 47, 3784-3786.
181. Epoxy-Annulations by Reactions of α-Amino Ketones with Vinyl Sulfonium Salts. Reagent Versus Substrate Control and Kinetic Resolution. (pdf)
M. G. Unthank, B. Tavassoli, V. K. Aggarwal,
Org. Lett., 2008, 10, 1501-1504.
180. Reactions of Silyl-Stabilised Sulfur Ylides with Organoboranes: Enantioselectivity, Mechanism, and Understanding. (pdf, 3.4Mb)
D. Howells, R. Robiette, G. Y. Fang, L. S. Knowles, M. D. Woodrow, J. N. Harvey, V. K. Aggarwal,
Org. Biomol. Chem., 2008, 6, 1185-1189.
179. Asymmetric Lithiation-Substitution of Amines Involving Rearrangement of Borates. (pdf)
I. Coldham, J.J. Patel, S. Raimbault, D. T. E. Whittaker, H. Adams, G. Fang, V. K. Aggarwal,
Org. Lett., 2008, 10, 141-143.
178. Application of Furyl-Stabilized Sulfur Ylides to a Concise Synthesis of 8a-epi-Swainsonine. (pdf)
J. Bi, V. K. Aggarwal,
Chem. Commun., 2008, 120-122.

2007

177. Chalcogenides as Organocatalysts
E. M. McGarrigle, E. L. Myers, O. Illa, M. A. Shaw, S. L. Riches, V. K. Aggarwal
Chem. Rev., 2007, 107, 5841-5883. doi | pdf
176. Ylide Based Reactions
V. K. Aggarwal, E. McGarrigle
in Handbook of Organocatalysis, P. Dalko (Ed.), Wiley-VCH, 2007, 357-390.
175. Trimethylsulfoxonium Iodide [first update]
E. M. McGarrigle, V. K. Aggarwal
in Encyclopedia of Reagents for Organic Synthesis [Online], L. A. Paquette (Ed.), John Wiley and Sons Ltd., 2007, doi
174. Mechanism of the Morita-Baylis-Hillman Reaction: A Computational Investigation.
R. Robiette, V. K Aggarwal, J. N. Harvey,
J. Am. Chem. Soc., 2007, 129, 15513-15525.
173. Asymmetric Sulfur Ylide Reactions with Boranes: Scope and Limitations, Mechanism and Understanding.
G. Y. Fang, O. A. Wallner, N. Di Blasio, X Ginesta, J. N. Harvey, V, K. Aggarwal,
J. Am. Chem. Soc., 2007, 129, 14632-14639.
172. A New Manifold for the Morita Reaction: Diene Synthesis from Simple Aldehydes and Acrylates/Acrylonitrile Mediated by Phosphines.
A. Palmelund, E. L. Myers, L. R. Tai, S. Tisserand, C. P. Butts, V. K. Aggarwal,
Chem. Commun., 2007, 4128-4130.
171. Lithiated Carbamates: Chiral Carbenoids for Iterative Homologation of Boranes and Boronic Esters.
J. L. Stymiest, G. Dutheuil, A. Mahmood, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2007, 46, 7491-7494
170. Aminals as Substrates for Sulfur Ylides: A Synthesis of Functionalised Aziridines and N-Heterocycles.
C. G. Kokotos, V. K. Aggarwal,
Org. Lett., 2007, 9, 2099-2102.
169. New Reaction of Cyclic Aminal with Michael Acceptors Leading to β-Amido-α,β-unstaurated Carbonyl Compounds through a Morita-Baylis-Hillman Type Reaction. Enantiocontrol and Applications in Synthesis.
E. Myers, H. de Vries, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2007, 46, 1893-1896
168. Asymmetric Synthesis of α-Substituted Allylic Boranes and their Application in Synthesis of iso-Agatharesinol.
G. Y. Fang, V. K. Aggarwal,
Angew. Chem. Int. Ed., 2007, 46, 359-362
167. Studies Towards a Biomimetic Synthesis of α-Cyclopiazonic Acid: Synthesis of 5-Substituted Isoxazole-4-carboxylic Esters.
V. A. Moorthie, E. M. McGarrigle, R. Stenson, V. K. Aggarwal,
Arkivoc, 2007, part V, 139-151.

2006

166. Rearrangements of Organozinc Compounds
V. K. Aggarwal, K. Sommer
in The Chemistry of Organozinc Compounds, Z. Rappoport and I. Marek (Eds.), S. Patai Series, J. Willey and Sons, 2006, 595-640. doi
165. Towards an Understanding of the Factors Responsible for the 1,2-Migration of Alkyl Groups in Borate Complexes
V. K. Aggarwal, G. Y. Fang, X. Ginesta, D. M. Howells, M. Zaja
Pure Appl. Chem., 2006, 78, 215-229. doi | pdf
164. Catalityc Asymmetric Sulfur Ylide Mediated Epoxidation of Carbonyl Compounds
V.K. Aggarwal
in Asymmetric Synthesis - The Essentials, M. Christmann, S. Brase (Eds.), Wiley-WCH, 2006, 52-56. doi
163. Asymmetric synthesis of epoxides and aziridines from aldehydes and imines
V. K. Aggarwal, M. D. Badine, V. A. Moorthie
in Aziridines and Epoxides in Organic Synthesis, A. K. Yudin (Ed.), Wiley-VCH: Weinheim, 2006, 1-34. doi
162. Dimethylsulfoxonium Methylide (1995)
V. K. Aggarwal, C. L. Winn
in Encyclopedia of Reagents for Organic Synthesis [Online], John Wiley and Sons Ltd., 15 Sep 2006, doi
161. Dimethylsulfonium Methylide (1995)
V. K. Aggarwal, C. L. Winn
in Encyclopedia of Reagents for Organic Synthesis [Online], John Wiley and Sons Ltd., 15 Sep 2006, doi
160. BF3·OEt2 and TMSOTf: A Synergistic Combination of Lewis Acids
E. Myers, C. P. Butts, V. K. Aggarwal,
Chem. Commun., 2006, 4434-4436.
159. The Use of Vinyl Sulfonium Salts in the Stereocontrolled Asymmetric Synthesis of Epoxide- and Aziridine-Fused Heterocycles: Application to the Synthesis of (-)Balanol
M. G. Unthank, N. Hussain, V.K. Aggarwal,
Angew. Chem. Int. Ed., 2006, 45, 7066-7069
158. A Practical Synthesis of a [2,2,1] Bicyclic Chiral Sulfide for Asymmetric Transformations
V. K. Aggarwal, G. Y. Fang, C. G. Kokotos, J. Richardson, M. G. Unthank , Tetrahedron, 2006, 62, 11297-11303.
157. Novel, Readily-Synthesised, Chiral Sulfides as Reagents for Asymmetric Epoxidation
D. M. Badine, C. Hebach, V. K. Aggarwal, Chem. Asian J., 2006, 1, 438-444.
156. Hemiaminals as Substrates for Sulfur Ylides: Direct Asymmetric Syntheses of Functionalised Pyrrolidines and Piperidines
C. Kokotos, V. K. Aggarwal,
Chem. Commun., 2006, 2156-2158.
155. Ligand Induced Control of C-H Versus C-C Insertion Reactions of Rh Carbenes
V. K. Aggarwal, T. Lecourt, C. G. Sheldon, M. Vitale, J. Am. Chem. Soc., 2006, 128, 2524-2525.
154. Reactivity and Selectivity in the Wittig Reaction: A Computational Study
R. Robiette, J. Richardson, V. K Aggarwal, J. N. Harvey, J. Am. Chem. Soc., 2006, 128, 2394-23.
153. Highly Enantioselective Synthesis of Glycidic Amides Using Camphor-Derived Sulfonium Salts. Mechanism and Applications in Synthesis
V. K. Aggarwal, J. P. H. Charmant, D. Fuentes, J. N. Harvey, G. Hynd, D. Ohara, W. Picoul, R. Robiette, C. Smith, J.-L. Vasse, C. L. Winn., J. Am. Chem. Soc., 2006, 128, 2105-2114.
152. Is phenyl a Good Migrating Group in the Rearrangement of Organoborates Generated from Sulfur Ylides?
R. Robiette, G. Y. Fang, J. N. Harvey, V. K. Aggarwal,
Chem. Commun., 2006, 741-743.
151. Delineation of the Factors Governing Reactivity and Selectivity in Epoxide Formation from Ammonium Ylides and Aldehydes
R. Robiette, M. Conza, V. K. Aggarwal,
Org. Biomol. Chem., 2006, 4, 621-623.
150. Optimization of the Mizoroki-Heck Reaction using Design of Experiment (DoE)
V. K. Aggarwal, A. C. Staubitz M. Owen, Org. Proc. Res. Dev., 2006, 10, 64-69.
149. Asymmetric Sulfonium Ylide Mediated Cyclopropanation: Stereocontrolled Synthesis of (+)-LY354740
V. K. Aggarwal, E. Grange, Chem. Eur. J., 2006, 12, 568-575.

2005

148. The Use of Tosylhydrazone Salts as a Safer Alternative to Handling Diazo Compounds and their Applications in Organic Synthesis
R. J. Fulton, V. K. Aggarwal, J. de Vicente
Eur. J. Org. Chem., 2005, 1479-1492. doi | pdf
147. α-Substituted Sulfur Ylides
V. K. Aggarwal, J. Richardson, C. L. Winn
in Science of Synthesis, A. B. Charette (Ed.), George Thieme Verlag, 2005, 22, 11-74.
146. Reagent Controlled Addition of Chiral Sulfur Ylides to Chiral Aldehydes
V. K. Aggarwal, J. Bi, Beilstein Journal of Organic Chemistry, 2005, 1, article 4. doi
145. On the Origin of High E Selectivity in the Wittig Reaction of Stabilized Ylides: Importance of Dipole-Dipole Interactions
R. Robiette, J. Richardson, V. K. Aggarwal, J. N. Harvey, J. Am. Chem. Soc., 2005, 127, 13468-13469.
144. Enantioselective α-Arylation of Cyclohexanones with Diaryl Iodonium Salts: Application to the Synthesis of (-)-Epibatidine
V. K. Aggarwal, B. Olofsson, Angew. Chem. Int. Ed., 2005, 44, 5516-5519.
143. Highly regioselective and Diastereoselective Epoxidation of Allylic amines with Oxone
V. K. Aggarwal, G. Y. Fang, Chem. Commun, 2005, 3448-3450.
142. Highly Diastereoselective Diels-Alder Reactions of Baylis-Hillman Adducts
V. K. Aggarwal, A. Patin, S. Tisserand, Org. Lett., 2005, 7, 2555-2557.
141. On the Importance of Leaving Group Ability in Reactions of Ammonium, Oxonium, Phosphonium and Sulfonium Ylides
V. K. Aggarwal, J. N. Harvey, R. Robiette, Angew. Chem. Int. Ed., 2005, 44, 5468-5471.
140. Carboxylate-Stabilised Sulfur Ylides (Thetin Salts) in Asymmetric Epoxidation for the Synthesis of Glycidic Acids. Mechanism and Implications
V.K. Aggarwal, C. Hebach, Org. Biomol. Chem., 2005, 3, 1419-1427.
139. Separation of Pyrrolidine Allylation Products by Diastereoselective Enzymatic Ester Hydrolysis
V. K. Aggarwal, C.J. Astle, H. Iding, B.Wirz, M. Rogers-Evans, Tetrahedron Lett., 2005, 46, 945-947.
138. Synthesis and Applications of Chiral Organoboranes Generated from Sulfonium Ylides
V. K Aggarwal, G. Yu Fang, A. Schmidt, J. Am. Chem. Soc., 2005, 127, 1642-1643. doi
137. Re-evaluation of the Mechanism of the Baylis-Hillman Reaction - Implications for Asymmetric Catalysis
V. K Aggarwal, S.Y. Fulford G. C. Lloyd-Jones, Angew. Chem. Int. Ed., 2005, 44, 1706-1708.
136. Simple Preparation of Trans-epoxides via Ylide Intermediates
V. K. Aggarwal, C. Aragoncillo, C. L. Winn, Synthesis, 2005, 1378-1382.

Pre-2005

135. Sulfur Ylides
V. K. Aggarwal, J. Richardson
in Science of Synthesis, A. Padwa, D. Bellus (Eds.), George Thieme Verlag, 2004, 27, 21-105.
134. Catalytic Asymmetric Sulfur Ylide-Mediated Synthesis of epoxidation of Carbonyl Compounds: Scope, Selectivity and Applications in Synthesis
V. K. Aggarwal, C. L. Winn
Acc. Chem. Res., 2004, 37, 611-620. doi | pdf
133. Lithiation and Reactions of Stilbene oxides: Synthetic Utility
V.K. Aggarwal, S. Florio, A. Salomon, Org. Lett., 2004, 6, 4191-4194.
132. Application of Sulfur Ylide Mediated Epoxidations in the Asymmetric Synthesis of β-Hydroxy-δ-Lactones. Synthesis of a Mevinic Acid Analogue and (+)-Prelactone B
V. K. Aggarwal, I. Bae, H.-Y.Lee, Tetrahedron, 2004, 60, 9725-9733. link
131. Asymmetric Synthesis of Avenaciolide via Cascade Palladium Catalysed Cyclisation-Carbonylation of Bromodienes
V. K. Aggarwal, P.W. Davies, A.T. Schmidt Chem. Commun. 2004, 1232-1233.
130. A Concise Asymmetric Route to the Bridged Bicyclic Tropane Alkaloid Ferruginine using Enyne Ring Closing Metathesis
V. K. Aggarwal, C. J. Astle, M. Rogers-Evans, Org. Lett.,2004, 6, 1469-1471.
129. Effect of Sulfide Structure on Enantioselectivity in Catalytic Asymmetric Epoxidation of Aldehydes; Mechanistic Insights and Implications
V. K. Aggarwal, J. Charmant, L. Dudin, M. Porcelloni, J. Richardson, Proc. Nat. Acad. Sciences, 2004, 5467-5471.
128. The Complexity of Catalysis: Origins of Enantio- and Diastereocontrol in Sulfur Ylide Mediated Epoxidation Reactions
V. K. Aggarwal, J. Richardson
Chem. Commun., 2003, 2644-2651. doi | pdf
127. Profile of V. K. Aggarwal
Org. Biomol. Chem., 2003, 1, 4x-4xi. doi | pdf
126. Catalytic Asymmetric Nazarov Reactions Promoted by Chiral Lewis Acid Complexes
V. K. Aggarwal, A. J. Belfield, Org. Lett., 2003, 5, 5075-5078.
125. Highly Diastereoselective Simmons-Smith Cyclopropanation of Allylic Amines
V. K. Aggarwal, G.-Y. Fang, G. Meek, Org. Lett., 2003, 5, 4417-4420.
124. Diastereoselective Synthesis of Cyclopropane Amino Acids Using Diazo Compounds Generated In Situ
L. A. Adams, V. K. Aggarwal, R. V. Bonnert, B. Bressel, R. J. Cox, J. Shepherd, J. de Vicente, M. Walter, W. Whittingham, J. Org. Chem., 2003, 68, 9433-9440.
123. Asymmetric Sulfur Ylide Mediated Aziridination: Application in the Synthesis of the Side Chain of Taxol
V. K. Aggarwal, J. L. Vasse, Org. Lett., 2003, 5, 2644-2651.
122. Tandem Formation and [2,3] Rearrangement of Methylene Ammonium Ylides Derived from Amines and the Simmons-Smith Reagent
V. K. Aggarwal, G. Fang, G. Meek, J. P. H. Charmant, Org. Lett. 2003, 5, 1757-1760.
121. Palladium catalysed cyclisation-carbonylation of enynes to give cyclic γ,δ-unsaturated acids
V. K. Aggarwal, M. Butters, P.W. Davies, Chem. Commun., 2003, 1046-1047.
120. Highly Diastereoselective 1,3-Dipolar Cycloaddition Reactions of trans-2-Methylene-1,3-dithiolane 1,3-dioxide with 3-Oxidopyiridinium and 3-Oxidopyrylium Betaines: a Route to the Tropane Skeleton
V. K. Aggarwal, R. S. Grainger, G. K. Newton, P. L. Spargo,A. D. Hobson and H. Adams, Org. Biomol. Chem., 2003, 1, 1884-1893. doi
119. Sulfur Ylide Mediated Synthesis of Highly Functionalised and Trisubstituted Epoxides with High Enantioselectivity. Application to the Synthesis of CDP 840
V. K. Aggarwal,I. Bae, H.-Y. Lee, D. T. Williams, Angew. Chem. Int. Ed., 2003, 42, 3274-3278. doi
118. A New Protocol for the in situ Generation of Aromatic, Heteroaromatic and Unsaturated Diazocompounds and its Application in Catalytic and Asymmetric Epoxidation of Carbonyl Compounds. Extensive Studies to map out Scope and Limitations and Rationalization of Diastereo- and Enantioselectivities
V. K. Aggarwal, E. Alonso, I. Bae, G. Hynd, K. M. Lydon, M. J. Palmer, M. Patel, M. Porcelloni, J. Richardson, R. Stenson, J. R. Studley, J.L. Vasse, C. L. Winn, J. Am. Chem. Soc., 2003, 125, 10926-40.
117. Highly Enantioselective Oxidations of Ketene Dithioacetals: Formation of Trans Bis-sulfoxides without Contamination from Meso Isomers
V. K. Aggarwal, R. M. Steele, Ritmaleni, J. K. Barrell, I. Grayson, J. Org. Chem. 2003, 68, 4087-4090.
116. A Novel One-pot Method for the Preparation of Pyrazoles by 1,3-Dipolar Cycloadditions of Diazo Compounds Generated In Situ
V. K. Aggarwal, J. de Vicente, J. Org. Chem. 2003, 68, 5381-5383.
115. Generation of Phosphoranes Derived from Phosphites. A New Class of Phosphorus Ylides Leading to High E Selectivity with Semi-Stabilizing Groups in Wittig Olefinations
V. K. Aggarwal, J. R. Fulton, C. G. Sheldon, J. de Vicente, J. Am. Chem. Soc., 2003, 125, 6034-6035.
114. New insights in the Mechanism of Amine Catalysed Epoxidation: Dual Role of Protonated Ammonium Salts as Both Phase Transfer Catalysts and Activators of Oxone
V. K. Aggarwal, C. Lopin, F. Sandrinelli, J. Am. Chem. Soc., 2003, 125, 7596-7601.
113. The use of Enantiomerically Pure Ketene Dithioacetal bis-Sulfoxides in Highly Diastereoselective Intramolecular Nitrone Cycloadditions. Application in the Total Synthesis of α-Amino Acids, (-)-Cispentacin and the First Asymmetric Synthesis of 4-Amino-pyrrolidine-3-carboxylic acid
V. K. Aggarwal, S. Roseblade, R. Alexander, Org. Biomol. Chem., 2003, 1, 684-691.
112. Correlation Between pKa and Reactivity of Quinuclidine-based Catalysts in the Baylis-Hillman Reaction - Discovery of Quinuclidine as Optimum Catalyst Leading to Substantial Enhancement of Scope
V. K. Aggarwal, I. Emme, S. Y. Fulford, J. Org. Chem. 2003, 68, 692-700.
111. Extension of Ring Closing Metathesis Methodology to the Synthesis of Carbocyclic Methyl and Silyl Enol Ethers
V. K. Aggarwal, A. M. Daly. Chem. Commun. 2002, 2490-2491.
110. Ketene Claisen Rearrangement of Camphor-derived 1,3-oxathianes: complete control of tertiary and quaternary stereogenic centres
V. K. Aggarwal; A. Lattanzi; D. Fuentes Chem. Commun. 2002, 2534-2535.
109. Application of the Chiral Acyl Anion Equivalent, trans-1,3-Dioxide, to an Asymmetric Synthesis of (R)-Salbutamol
V. K. Aggarwal, B. N. Esquivel-Zamora J. Org. Chem. 2002, 67, 8618-8621.
108. A palladium catalysed cyclisation-carbonylation of bromodienes: control in carbonylation over facile beta-hydride elimination
V. K. Aggarwal; P. W. Davies; W. O. Moss Chem. Commun. 2002,43, 972-973.
107. Sulphur ylide-mediated stereoselective synthesis of a stable ferrocenyl epoxide
M. Catasus; A. Moyano; V. K. Aggarwal Tetrahedron Lett. 2002,43, 3475-3479.
106. Unraveling the mechanism of epoxide formation from sulfur ylides and aldehydes
V. K. Aggarwal; J. N. Harvey; J. Richardson J. Am. Chem. Soc. 2002,124, 5747-5756.
105. Synthesis of epoxides from aldehydes and tosylhydrazone salts catalysed by triphenylarsine: complete trans selectivity for all combinations of coupling partners
V. K. Aggarwal; M. Patel; J. Studley Chem. Commun. 2002, 1514-1515.
104. Unexpected side reactions of imidazolium-based ionic liquids in the base-catalysed Baylis-Hillman reaction
V. K. Aggarwal; I. Emme; A. Mereu Chem. Commun. 2002, 1612-1613.
103. Highly enantioselective Darzens reaction of a camphor-derived sulfonium amide to give glycidic amides and their applications in synthesis
V. K. Aggarwal; G. Hynd; W. Picoul; J. L. Vasse J. Am. Chem. Soc. 2002,124, 9964-9965.
102. A new method for the preparation of silyl enol ethers from carbonyl compounds and (Trimethylsilyl)diazomethane in a regiospecific and highly stereoselective manner
V. K. Aggarwal; C. G. Sheldon; G. J. Macdonald; W. P. Martin J. Am. Chem. Soc. 2002,124, 10300-10301.
101. Epoxidation of alkenes by amine catalyst precursors: Implication of aminium ion and radical cation intermediates (vol 122, pg 8317, 2000)
M. F. A. Adamo; V. K. Aggarwal; M. A. Sage J. Am. Chem. Soc. 2002,124, 11223-11223.
100. Synthesis of new, highly hindered C-2-symmetric trans (2S,5S)- disubstituted pyrrolidines
V. K. Aggarwal; F. Sandrinelli; J. P. H. Charmant Tetrahedron Asymm. 2002,13, 87-93.
99. Highly diastereoselective aziridination of imines with trimethylsilyldiazomethane. Subsequent silyl substitution with electrophiles, ring opening, and metalation of C- silylaziridines - A cornucopia of highly selective transformations
V. K. Aggarwal; E. Alonso; M. Ferrara; S. E. Spey J. Org. Chem. 2002,67, 2335-2344.
98. Highly diastereoselective nitrone cycloaddition onto a chiral ketene equivalent: Asymmetric synthesis of cispentacin
V. K. Aggarwal; S. J. Roseblade; J. K. Barrell; R. Alexande Org. Lett. 2002,4, 1227-1229.
97. The use of enantiomerically pure N-sulfinimines in asymmetric Baylis-Hillman reactions
V. K. Aggarwal; A. M. M. Castro; A. Mereu; H. Adams Tetrahedron Lett. 2002,43, 1577-1581.
96. Rate Acceleration of the Baylis-Hillman Reaction in Polar Solvents (Water and Formamide). Dominant Role of Hydrogen Bonding not Hydrophobic Effects are Implicated
V. K. Aggarwal; D. K. Dean; A. Mereu, R. Williams J. Org. Chem. 2002,67, 510-514.
95. Developments in the Simmons-Smith Mediated Epoxidation Reaction
V. K. Aggarwal; M. P. Coogan; R. A. Stenson; R. V. H. Jones; R. Fieldhouse; J. Blacker Eur. Jn. Org. Chem. 2002, 319-326.
94. Additions of stabilised and semi-stabilised sulfur ylides to tosyl protected imines: are they under kinetic or thermodynamic control?
V. K. Aggarwal; J. P. H. Charmant; C. Ciampi; J. M. Hornby; C. J. O'Brien; G. Hynd; R. Parsons J. Chem. Soc., Perkin Trans. 1 2001, 3159-3166.
93. Synthesis and evaluation of a broad range of chiral sulfides for asymmetric sulfur ylide epoxidation of aldehydes
V. K. Aggarwal; R. Angelaud; D. Bihan; P. Blackburn; R. Fieldhouse; S. J. Fonquerna; G. D. Ford; G. Hynd; E. Jones; R. V. H. Jones; P. Jubault; M. J. Palmer; P. D. Ratcliffe; H. Adams J. Chem. Soc., Perkin Trans. 1 2001, 2604-2622.
92. Catalytic Cyclopropanation of Alkenes using Diazo Compounds Generated In Situ. A novel route to 2-Arylcyclopropylamines
V. K. Aggarwal; J. de Vicente; R. V. Bonnert Org. Lett. 2001, 3, 2785-2788.
91. A novel procedure for the synthesis of aziridines: application of Simmons-Smith reagents to aziridination
V. K. Aggarwal; R. A. Stenson; R. V. H. Jones; R. Fieldhouse; J. Blacker Tetrahedron Lett. 2001, 42, 1587-1589.
90. Scope and limitations in sulfur ylide mediated catalytic asymmetric aziridination of imines: use of phenyldiazomethane, diazoesters and diazoacetamides
V. K. Aggarwal; M. Ferrara; C. J. O'Brien; A. Thompson; R. V. H. Jones; R. Fieldhouse J. Chem. Soc., Perkin Trans. 1 2001, 1635-1643.
89. Application of Chiral Sulfides to Catalytic Asymmetric Aziridination and Cyclopropanation with in situ Generation of the Diazocompound
V. K. Aggarwal, E. Alonso, G. Fang, M. Ferrara, G. Hynd, and M. Porcelloni, Angew. Chem. Int. Ed., 2001, 41, 1433-1436.
88. Catalytic Asymmetric Synthesis of Epoxides from Aldehydes using Sulfur Ylides with in situ Generation of Diazocompounds
V. K. Aggarwal, E. Alonso, G. Hynd, K.M. Lydon, M.J. Palmer, M. Porcelloni,, J. R. Studley Angew. Chem. Int. Ed., 2001, 41, 1430-1433.
87. Profile of Professor Varinder K. Aggarwal (Corday Morgan Award)
V. K. Aggarwal
J. Chem. Soc., Perkin Trans. 1, 2000, 11, IX-X.
86. A simple, user-friendly process for the homologation of aldehydes using tosylhydrazone salts
V. K. Aggarwal, J. de Vicente, B. Pelotier, I. P. Holmes, R. V. Bonnert, Tetrahedron Lett., 2000, 41, 10327-10331.
85. Highly Selective Aziridination of Imines Using Trimethylsilyldiazomethane and Applications of C-Silylaziridines in Synthesis
Org. Lett.; 2000, 2, 4107-4110;
84. Amidine-promoted addition of chloroform to carbonyl compounds
V. K. Aggarwal; A. Mereu J. Org. Chem. 2000, 65, 7211-7212.
83. Epoxidation of alkenes by amine catalyst precursors: Implication of aminium ion and radical cation intermediates
M. F. A. Adamo; V. K. Aggarwal; M. A. Sage J. Am. Chem. Soc. 2000, 122, 8317-8318.
82. Catalytic cyclopropanation of electron deficient alkenes mediated by chiral and achiral sulfides: scope and limitations in reactions involving phenyldiazomethane and ethyl diazoacetate
V. K. Aggarwal; H. W. Smith; G. Hynd; R. V. H. Jones; R. Fieldhouse; S. E. Spey J. Chem. Soc., Perkin Trans. 1 2000, 3267-3276.
81. Stereochemical control in the synthesis of tetrahydrofurans by cyclisation of diols with [1,2]-phenylsulfanyl migration
V. K. Aggarwal; J. Eames; M. J. Villa; S. McIntyre; F. H. Sansbury; S. Warren J. Chem. Soc., Perkin Trans. 1 2000, 533-546
80. Copper(II)-bisoxazoline-catalysed asymmetric Diels-Alder reactions of alpha-thioacrylates
V. K. Aggarwal; D. E. Jones; A. M. Martin-Castro European Journal of Organic Chemistry 2000, 2939-2945.
79. Epoxidation of Aldehydes and Enones
V. K. Aggarwal
in Comprehensive Asymmetric Catalysis, E.N. Jacobsen, A. Pfaltz, H. Yamamoto (Eds.), Springer, 1999, Vol. II, 679-697. doi
78. Sulfur Ylide Mediated Catalytic Asymmetric Epoxidation and Aziridination
V. K. Aggarwal, J. G. Ford, A. Thompson, J. Studley, R. V. H. Jones, R. Fieldhouse
in Current Trends in Organic Synthesis, C. Scolastico, F. Nicotra (Eds.), Academic Press, New York, 1999, 191-199. doi
77. The Development and Use of Ketene Equivalents in [4+2] Cycloadditions for Organic Synthesis
V. K. Aggarwal, A. Ali, M. P. Coogan
Tetrahedron, 1999, 55, 293-312. doi | pdf
76. Diastereomerically pure spirocyclic bis-sulfinyl oxiranes and their application to the asymmetric synthesis of alpha-amino amides
V. K. Aggarwal; J. K. Barrell; J. M. Worrall; R. Alexander Phosphorus Sulfur 1999, 153, 337-338.
75. A formal synthesis of (+)-pyripyropene A using a biomimetic epoxy- olefin cyclisation: effect of epoxy alcohol/ether on cyclisation efficiency
V. K. Aggarwal; P. A. Bethel; R. Giles J. Chem. Soc., Perkin Trans. 1 1999, 3315-3321.
74. [2,3]-Sigmatropic Rearrangement of Allylic Sulfur Ylides Derived from Trimethylsilyldiazomethane (TMSD)
V. K. Aggarwal, M. Ferrara, R. Hainz, S. E. Spey, Tetrahedron Lett. 1999, 40, 8923-8927.
73. Enantioselective deprotonation of 4-tert-butylcyclohexanone by conformationally constrained chiral lithium amide bases
V. K. Aggarwal; P. S. Humphries; A. Fenwick J. Chem. Soc., Perkin Trans. 1 1999, 2883-2889.
72. Superior amine catalysts for the Baylis-Hillman reaction: the use of DBU and its implications
V. K. Aggarwal; A. Mereu J. Chem. Soc., Chem. Commun. 1999, 2311-2312.
71. An improved resolution of 2-methyl piperidine and its use in the synthesis of homochiral trans-2,6-dialkyl piperidines
M. F. A. Adamo; V. K. Aggarwal; M. A. Sage Synth. Comm. 1999, 29, 1747-1756.
70. A Formal Asymmetric Synthesis of (+)-Anatoxin-a Using an Enantioselective Deprotonation Strategy on an Eight Membered Ring
V. K. Aggarwal, P. S. Humphries, A. Fenwick Angew. Chem. Int. Ed., 1999, 38, 1985-1986.
69. A formal synthesis of (+)-pyripyropene A using a biomimetic epoxy- olefin cyclisation
V. K. Aggarwal; P. A. Bethel; R. Giles J. Chem. Soc., Chem. Commun. 1999, 325-326.
68. The effects of different ester and ketal protecting groups on the reactivity and selectivity of tartrate-derived silylketene acetals
V. K. Aggarwal; S. J. Masters; H. Adams; S. E. Spey; G. R. Brown; A. J. Foubister J. Chem. Soc., Perkin Trans. 1 1999, 155-162.
67. Direct Asymmetric Epoxidation of Aldehydes using Catalytic Amounts of Enantiomerically Pure Sulfides
V. K. Aggarwal, J. G. Ford, A. Thompson, R. V. H. Jones, M. C. H. Standen
in Selective Reactions of Metal-Activated Molecules, H. Werner, P. Schreier (Eds.), Vieweg, Gottingen, 1998, 13-24. doi
66. Sc(OTf)3, an efficient catalyst for addition of allyltrimethylsilane to aldehydes; Chemoselective addition to aldehydes in presence of ketones and in situ acylation (3 component coupling)
V. K. Aggarwal; G. P. Vennall Synthesis 1998, 1822-1826.
65. Studies on the asymmetric oxidation of ester derivatives of 1,3- dithiane-2-carboxylates. Asymmetric synthesis of trans-1,3-dithiane 1,3-dioxide
V. K. Aggarwal; B. N. Esquivel-Zamora; G. R. Evans; E. Jones J. Org. Chem. 1998, 63, 7306-7310.
64. Metal- and ligand-accelerated catalysis of the Baylis-Hillman reaction
V. K. Aggarwal; A. Mereu; G. J. Tarver; R. McCague J. Org. Chem. 1998, 63, 7183-7189.
63. Highly diastereoselective epoxidation of ketene dithioacetal dioxides: A new approach to the asymmetric synthesis of alpha-amino amides
V. K. Aggarwal; J. K. Barrell; J. M. Worrall; R. Alexander J. Org. Chem. 1998, 63, 7128-7129.
62. Catalytic Sylfur Ylide Reactions: Use of Diazoacetamides for the Diastereoselective Synthesis of Glycidic Amides
V. K. Aggarwal; P. B. Blackburn; R. V. H. Jones; R. Fieldhouse Tetrahedron Lett. 1998, 39, 8517-8520.
61. Catalytic asymmetric Diels-Alder reactions of alpha-thioacrylates for the preparation of norbornenone
V. K. Aggarwal; E. S. Anderson; D. E. Jones; K. B. Obierey; R. Giles Chemical Communications 1998, 1985-1986.
60. (1R,3R)-2-methylene-1,3-dithiolane 1,3-dioxide: a highly reactive and highly selective chiral ketene equivalent in cycloaddition reactions with a broad range of dienes
V. K. Aggarwal; Z. Gultekin; R. S. Grainger; H. Adams; P. L. Spargo J. Chem. Soc., Perkin Trans. 1 1998, 2771-2781.
59. Catalytic asymmetric epoxidation of aldehydes. Optimization, mechanism, and discovery of stereoelectronic control involving a combination of anomeric and Cieplak effects in sulfur ylide epoxidations with chiral 1,3-oxathianes
V. K. Aggarwal; J. G. Ford; S. Fonquerna; H. Adams; R. V. H. Jones; R. Fieldhouse J. Am. Chem. Soc. 1998 120, 8328-8339.
58. Sc(OTf)3, an efficient catalyst for formation and deprotection of geminal diacetates (acylals); Chemoselective protection of aldehydes in presence of ketones
V. K. Aggarwal; S. Fonquerna; G. P. Vennall Synlett 1998, 849-852.
57. Bifunctional catalysts for catalytic asymmetric sulfur ylide epoxidation of carbonyl compounds
V. K. Aggarwal; L. Bell; M. P. Coogan; P. Jubault J. Chem. Soc., Perkin Trans. 1 1998, 2037-2042.
56. 1,3-Dipolar cycloaddition reactions of trans-2-methylene-1,3- dithiolane 1,3-dioxide with nitrones
V. K. Aggarwal; R. S. Grainger; H. Adams; P. L. Spargo J. Org. Chem. 1998, 63, 3481-3485
55. Camphor Derived 1,4-Oxathianes for Carbonyl Epoxidation
V. K. Aggarwal, J. G. Ford, R. V. H. Jones, R. Fieldhouse, Tetrahedron Asymm. 1998, 9, 1801-1807.
54. Catalytic Asymmetric Epoxidation and Aziridination Mediated by Sulfur Ylides. Evolution of a Project
V. K. Aggarwal,
Synlett, 1998, 329-336.
53. Scandium trifluoromethanesulfonate, an efficient catalyst for the intermolecular carbonyl-ene reaction and the intramolecular cyclisation of citronellal
V. K. Aggarwal; G. P. Vennall; P. N. Davey; C. Newman Tetrahedron Lett. 1998, 39, 1997-2000.
52. Asymmetric Ylide Reactions: Epoxidation, Cyclopropanation, Aziridination, Olefination, and Rearrangement
A.-H. Li, L.-X. Dai, V. K. Aggarwal
Chem. Rev., 1997, 97, 2341-2372. doi | pdf
51. A novel procedure for the synthesis of epoxides: Application of Simmons-Smith reagents toward epoxidation
V. K. Aggarwal; A. Ali; M. P. Coogan J. Org. Chem. 1997, 62, 8628-8629.
50. Trans-1,3-Dithiane-1,3-Dioxide; a Chiral Acyl Anion Equivalent. Enantioselective Synthesis of ?-Hydroxy-Carboxylic Acids, Esters, Amides and Ketones
V. K. Aggarwal, A. Thomas, S. Schade, Tetrahedron, 1997, 16213-16228.
49. Catalytic Asymmetric Cyclopropanation of Electron Deficient Alkenes Mediated By Chiral Sulfides.
V. K. Aggarwal, H. W. Smith, R. V.H. Jones, R. Fieldhouse, J. Chem. Soc., Chem. Commun. 1997, 1785-1786.
48. Dimethylsulfonium 9-Fluorenide - Solution Structure and Dynamic Behaviour of a Semi-Stabilised Sulfonium Ylide
V. K. Aggarwal, S. Schade, B. Taylor, J. Chem. Soc., Perkin Trans. 1 1997, 2811-2813.
47. Asymmetric total synthesis of (+)-carbocyclic uracil polyoxin C
V. K. Aggarwal, N. Monteiro, J. Chem. Soc., Perkin Trans. 1 1997, 2531-2537.
46. Scope and Limitations in Palladium Catalysed Substitution Reactions of Unsaturated Fused Lactones
V. K. Aggarwal, N. Monteiro, G. J. Tarver, R. McCague, J.Org. Chem. 1997, 4665-4671.
45. Trifluoromethanesulfonic Acid, an Efficient Catalyst for the Hetero Diels-Alder Reaction and an Improved Synthesis of Mefrasol
V. K. Aggarwal, G. P. Vennall, P. N. Davey, C. Newman, Tetrahedron. Lett. 1997, 2569-2572.
44. Addition of Benzyl Sulfonium Ylides to Aldehydes and Ketones. Are they under Kinetic or Thermodynamic Control?
V. K. Aggarwal, S. Calamai, J. G. Ford, J. Chem. Soc., Perkin Trans. 1 1997, 593-599.
43. Electronic Conference on Organometallic Chemistry: Catalytic Asymmetric Epoxidation
V.K. Aggarwal, J. G. Ford, P. Blackburn, http://www.ch.ic.ac.uk/ectoc/ectoc-3/, June-July 1997.
42. Seminars in Organic Synthesis: Asymmetric Epoxidation, XXII Summer School, Gargnano, Società Chimica Italiana
V. K. Aggarwal, J. G. Ford, 1997, 7-50.
41. Catalytic and Asymmetric Aziridination Using Sulfur Ylides
V. K. Aggarwal, A. Thompson, R. V. H. Jones, and M. C. H. Standen, Phosphorus Sulfur 1997, 120, 361-362.
40. Stereselective Epoxidation of bis-Sulfinyl Alkenes and Applications to the Asymmetric Synthesis of ?-Substituted Carboxylic Acids
V. K. Aggarwal, J. M. Worrall, R. Alexander, Phosphorus Sulfur 1997, 120, 351-352.
39. Anion Reactions of Trans-1,3-Dithiolane-1,3-Dioxide with Aldehydes and Comparison with Trans-1,3-Dithiane-1,3-Dioxide
V. K. Aggarwal, S. Schade, H. Adams, J.Org. Chem. 1997, 62, 1139-1145.
38. Direct Measurement of the Anomeric Effect in Sulfoxides: Conformational Analysis and X-Ray crystal Structures of 2-Halo-1,3-Dithiane-trans-1,3-Dioxide
V. K. Aggarwal, J. M. Worrall, H. Adams, R. Alexander, J. Chem. Soc., Perkin Trans. 1 1997, 21-24.
37. 2-Halo-1,3-Dithiane-1,3-Dioxide : a Diastereoselective Carbonyl Anion Equivalent in Reactions with Aldehydes
V. K. Aggarwal, G. Boccardo, J. M. Worrall, Harry Adams, R. Alexander, J. Chem. Soc., Perkin Trans. 1 1997, 11-19.
36. First Examples of Metal and Ligand Accelerated Catalysis of the Baylis Hillman Reaction
V. K. Aggarwal, G. J. Tarver, R. McCague J. Chem. Soc., Chem. Commun. 1996, 2713-2714.
35. Novel Catalytic and Asymmetric Process for Aziridination Mediated by Sulfur Ylides
V. K. Aggarwal, A. Thompson, R. V. H. Jones, and M. C. H. Standen, J.Org. Chem. 1996, 61, 8368-8369.
34. Direct Asymmetric Epoxidation of Aldehydes Using Catalytic Amounts of Enantiomerically Pure Sulfides
V. K. Aggarwal, J. G. Ford, A. Thompson, R. V. H. Jones, and M. C. H. Standen, J. Am. Chem. Soc. 1996, 118, 7004-7005.
33. First Synthesis and X-ray Crystal Structure of 1,2-(1,1'-Ferrocenediyl)ethene
V. K. Aggarwal, D. Jones, M. L.Turner and H. Adams, J. Organomet. Chem., 1996, 524, 263-266.
32. A Novel Catalytic Cycle For The Synthesis Of Epoxides Using Sulfur Ylides
V. K. Aggarwal; H. Abdel-Rahman; Li Fan, R. V. H. Jones; M. C. H. Standen, Chemistry, A Eurpoean Journal, 1996, 2, 1024-1030.
31. Scandium Trifluoromethanesulfonate, a Novel Catalyst for the Addition of Allyltrimethylsilane to Aldehydes
V. K. Aggarwal, G. P. Vennall, Tetrahedron. Lett. 1996, 3745-3746.
30. Palladium-Catalyzed Substitution Of Unsaturated Lactones - Application to the Synthesis Of Carbocyclic Polyoxins and Nikkomycins
V. K. Aggarwal; N. Monteiro; G. J. Tarver; S. D. Lindell J. Org. Chem. 1996, 61, 1192-1193.
29. Catalytic Asymmetric Synthesis of Epoxides Mediated by Chiral Iminium Salts
V. K. Aggarwal; M. F. Wang J. Chem. Soc., Chem. Commun. 1996, 191-192.
28. The Use Of Chiral Sulfides In Catalytic Asymmetric Epoxidation
V. K. Aggarwal; A. Thompson; R. V. H. Jones; M. Standen Tetrahedron Asymm. 1995, 6, 2557-2564.
27. (1R,3R)-2-Methylene-1,3-Dithiolane 1,3-Dioxide - a Highly Reactive and Highly Selective Chiral Ketene Equivalent
V. K. Aggarwal; J. Drabowicz; R. S. Grainger; Z. Gultekin; M. Lightowler; P. L. Spargo J. Org. Chem. 1995, 60, 4962-4963.
26. Anion reactions of 1,3-dithiane 1,3-dioxide with carbonyl-compounds - high diastereoselectivity with aromatic-aldehydes under conditions of equilibrium control
V. K. Aggarwal; R. Franklin; J. Maddock; G. R. Evans; A. Thomas; M. F. Mahon; K. C. Molloy; M. J. Rice J. Org. Chem. 1995, 60, 2174-2182.
25. Complexes Containing a Lewis-Acid and Bronsted Acid For the Catalytic Asymmetric Diels-Alder Reaction
V. K. Aggarwal; E. Anderson; R. Giles; A. Zaparucha Tetrahedron-Asymmetry 1995, 6, 1301-1306.
24. A Novel Catalytic Cycle For the Synthesis Of Epoxides Using Sulfur Ylides - Application to Base Sensitive Aldehydes
V. K. Aggarwal; H. Abdel-Rahman; R. V. H. Jones; M. C. H. Standen Tetrahedron. Lett. 1995, 36, 1731-1732.
23. A novel catalytic cycle for the synthesis of epoxides using sulfur ylides, and application to the synthesis of cyclopropanes and aziridines V. K. Aggarwal; H. Abdel-Rahman; A. Thompson; B. Mattison; R. V. H. Jones Phosphorus Sulfur 1995, 283-292.
22. Synthesis of Sulfonium Salts by Sulfide Alkylation; an Alternative Approach
V. K. Aggarwal; A. Thompson; R. V. H. Jones Tetrahedron. Lett. 1994, 8659-8660.
21. Asymmetric-Synthesis and Cycloaddition Chemistry Of Trans-2- Methylene-1,3-Dithiolane 1,3-Dioxide
V. K. Aggarwal; R. S. Grainger; P. L. Spargo Phosphorus Sulfur 1994, 95, 337-338.
20. Studies on the oxidation of 1,3-dithiane and 5,5-disubstituted analogues including X-ray crystal structure, equlibration studies and pKa measurements on selected oxides
V. K. Aggarwal; I. W. Davies; R. Franklin; J. Maddock; M. F. Mahon; K. C. Molloy J. Chem. Soc., Perkin Trans. 1 1994, 2363-2368.
19. Stereoselective Addition Reactions of Lithiated 2-Chloro-1,3-Dithiane-1,3-Dioxide to Aldehydes
V. K. Aggarwal, J.M. Worrall, H. Adams, R. Alexander, Tetrahedron Letters, 1994, 35, 6167-6170.
18. Trans-1,3-dithiane-1,3-dioxide, a new chiral acyl anion equivalent for the preparation of masked activated acids - application to the synthesis of alpha-hydroxy acid-derivatives
V. K. Aggarwal; A. Thomas; R. J. Franklin J. Chem. Soc. , Chem. Commun. 1994, 1653-1654.
17. Novel catalytic cycle for the synthesis of epoxides from aldehydes and sulfur ylides mediated by catalytic quantities of sulfides and Rh2(OAc)4
V. K. Aggarwal, H. Abdel-Rahman, R. V. H. Jones, H. Y. Lee, B. D. Reid, J. Am. Chem. Soc. 1994, 116, 5973-5974.
16. Asymmetric epoxidation using chiral sulfur ylides
V. K. Aggarwal; M. Kalomiri; A. P. Thomas Tetrahedron Asymm. 1994, 5, 723-730.
15. The First Synthesis of the Novel 2,8-Dioxobicyclo[3,2,1]octane Ring System - a Key Feature of the Squalestatins
V. K. Aggarwal, M. F. Wang, A. Zaparucha, J. Chem. Soc., Chem. Commun., 1994, 87-88.
14. Enantioselective Transformations and Racemisation Studies of Heteroatom Substituted Organolithium Compounds
13. Chiral Ketene Equivalents for use in Asymmetric Synthesis
V. K. Aggarwal, M. Lightowler, Phos., Sulfur and Silicon, 1993, 74, 407-408.
12. Chiral, Bisfunctionalisation of Substrates: a Powerful Strategy for the Asymmetric Synthesis of C2 Symmetric Compounds and its Application to the Synthesis of Enantiomerically Pure Trans-1,3-dithiane-1,3-dioxide 1
V. K. Aggarwal, E. Moya, G. Evans, J. Dowden, J. Org. Chem. 1992, 57, 6390-6391.
11. Trans-Dioxides of Cyclic Ketene Thioacetals: Highly Selective Chiral Ketene Equivalents
V. K. Aggarwal, M. Lightowler, S.D. Lindell Synlett., 1992, 730-732.
10. Highly Stereoselective Addition Reactions of Metallated Trans-1,3-dithiane-1,3-dioxide to Aldehydes
V. K. Aggarwal, R. J. Franklin, M. J. Rice, Tetrahedron Letters, 1991, 32, 7743-7746.
9. Synthesis, X-ray Crystal Structure, Equilibration Studies, and Anion Chemistry of Trans-1,3-dithiane-1,3-dioxide
V. K. Aggarwal, I. W. Davies, R. J, Franklin, J. Maddock, M. F. Mahon, K. C. Molloy, J. Chem. Soc., Perkin Commun., 1991,662-664.
8. Transformation of Cyclic a-Phenylthio Aldehydes by Stereoselective Aldol Reactions and Phenylthio Migration into Spirocyclic Lactones and Ethers, and E-Allylic Alcohols with 1,4-Related Chiral Centres
V. K. Aggarwal, I Coldham, S. McIntre and S. Warren, J. Chem. Soc., Perkin Trans. 1, 1991, 451-460.
7. Trans-1,3-Dithiane-1,3-dioxide as a Potential Chiral Acyl Anion Equivalent
V. K. Aggarwal, R. J, Franklin in 'Chirality in Drug Design and Synthesis' C. Brown (Ed), Academic Press, London, 1990, 229-230.
6. Additions of Aldehydes to Metallated Trans-1,3-dithiane-S,S-dioxide Under Conditions of Kinetic and Thermodynamic Control
V. K. Aggarwal, I. W. Davies, J. Maddock, M. F. Mahon, K. C. Molloy, Tetrahedron Letters, 1990, 31, 135-138.
5. Stereochemical Control in the Synthesis of Tetrahydrofurans by Cyclisation of Diols with Phenylthio Migration
V. K. Aggarwal, I Coldham, S. McIntre, F. H. Sansbury, M.-J. Villa and S. Warren, Tetrahedron Letters, 1988, 29, 4885-4888.
4. A Review of S. G. Warren's Recent Work
V. K. Aggarwal
Chemical Highlights, 1987, 208-215.
3. Synthesis of Compounds with 1,4-Related Chiral Centres by Phenylthio Migration: Syn and Anti-E-2,4 Dimethylhex-3-ene-1,5-Diol
V. K. Aggarwal and S. Warren, Tetrahedron Letters, 1987, 28, 1925-1928.
2. Allyl Sulphide Synthesis by Phenylthio Migration: Relationship between Stereochemistry of Starting Material and Regioselectivity of Double Bond Formation
V. K. Aggarwal and S. Warren, J. Chem. Soc., Perkin Trans. 1, 1987, 2579-2584.
1. Phenylthio (PhS) Migration in the Stereocontrolled Synthesis of Allylic Alcohols with 1,4-Related Chiral Centres
V. K. Aggarwal and S. Warren, Tetrahedron Letters, 1986, 27, 101-104.